Capryloyl Glycine And Soy Isoflavonoids In Hypertrichosis: An Experimental And Placebo-Controlled Clinical Study

The study evaluated a cream containing 4% capryloyl glycine and 1% soy isoflavonoids for its ability to inhibit ODC1 activity and manage hypertrichosis in 12 Caucasian female patients. The cream was applied to the right forearm, while a placebo was applied to the left forearm. Results showed that the cream significantly inhibited ODC1 activity by 35.1% and led to improvement in 91.7% of patients, with good efficacy in 58.3% and moderate efficacy in 41.7%. No improvement was observed with the placebo, indicating the cream's effectiveness in reducing hair growth on the forearms.