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    GlossaryOrnithine Decarboxylase Inhibitors

    compounds that block an enzyme crucial for cell growth

    Ornithine Decarboxylase Inhibitors (ODC Inhibitors) are compounds that block the activity of the enzyme ornithine decarboxylase, which is crucial for the production of polyamines. Polyamines are molecules that play a key role in cell growth and differentiation. By inhibiting this enzyme, ODC Inhibitors can potentially slow down or prevent the proliferation of cells, making them useful in treatments for conditions like cancer and certain types of hair loss, such as androgenetic alopecia.

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      Contemporary medical therapy for polycystic ovary syndrome

      research Contemporary medical therapy for polycystic ovary syndrome

      31 citations ,   September 2006 in “International journal of gynaecology and obstetrics”
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      research Hirsutism: from Brazil to a place near you

      3 citations ,   January 2010 in “Expert Opinion on Pharmacotherapy”
      No treatment fully stops excessive hair growth in women, but various methods can help manage it effectively.
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      67 citations ,   July 2006 in “Clinics in Dermatology”
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      PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.
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        January 2014 in “John Wiley & Sons, Ltd eBooks”
      The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
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      106 citations ,   April 2010 in “ACS Nano”
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      research Diagnosis and treatments of hirsutism: where are we?

      3 citations ,   August 2011 in “Expert Review of Dermatology”
      Effective treatments for excessive hair growth in women include creams, laser therapy, and medications, with the choice depending on individual needs and potential side effects.
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      47 citations ,   August 2000 in “Endocrine Reviews”
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        October 2018 in “Springer eBooks”
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      19 citations ,   July 2006 in “Lasers in medical science”
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      Drug Discovery Today: Therapeutic Strategies - 2006 Editorial

      research Drug Discovery Today: Therapeutic Strategies - 2006 Editorial

        March 2006 in “Drug Discovery Today: Therapeutic Strategies”
      The 2006 editorial concluded that immunotherapy was advancing with new drugs, focusing on specific biological therapies and convenient oral treatments, and highlighted the importance of partnerships and new regulations in the field.
      Medications

      research Medications

        January 2016 in “Springer eBooks”
      Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.
      Cytostatics and immunosuppressive drugs

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        January 1989 in “Side effects of drugs annual”
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      research ENZYMES

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      66 citations ,   September 2008 in “Dermatologic therapy”
      The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.