January 2022 in “World journal of pharmaceutical sciences” In this study, irregular menstruation was observed as the most common clinical manifestation of polycystic ovarian disorder in the subjects, followed by dermatologic symptoms like hirsutism and acne.
1 citations
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March 2025 in “Medical Molecular Morphology” This review discusses how androgens, commonly known for male reproductive roles, also influence the physiology and pathology of the human endometrium, though their exact roles in this tissue remain controversial and not fully understood.
378 citations
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November 2011 in “Human reproduction update” This review discusses the epidemiology, causes, diagnosis, and management of hirsutism in women, noting that effective treatment requires addressing the root cause as well as the hair growth.
3 citations
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July 2019 in “Case Reports in Obstetrics and Gynecology” This case report and literature review describes a 27-year-old woman with a Sertoli Leydig cell tumor causing testosterone-related symptoms and highlights normalization of hormone levels after surgical treatment.
120 citations
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April 2019 in “The Journal of clinical investigation/The journal of clinical investigation” This review discusses the roles estrogens play in males and androgens in females, challenging the traditional view of strictly "male" and "female" hormones, but it does not report new experimental findings.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this cross-sectional study at a tertiary care hospital, researchers found a significant correlation between cutaneous manifestations like hirsutism and acne and biochemical hyperandrogenism levels in women with PCOS, suggesting these skin conditions can predict elevated androgen levels.
June 2022 in “Evidence-based complementary and alternative medicine” This study found that acupressure on specific points improved health-related quality of life and reduced total testosterone levels and clinical symptoms in patients with polycystic ovary syndrome compared to controls.
15 citations
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October 2018 in “Reproductive Biomedicine Online” This study suggests that the anogenital distance measure AGDAC may moderately discriminate the presence of polycystic ovarian syndrome and could be a useful clinical tool.
12 citations
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February 2020 in “The Journal of Clinical Endocrinology & Metabolism” This study found that a self-assessed modified Ferriman-Gallwey score of 10 or higher indicates excess body hair, and suggests androstenedione measurement should accompany testosterone when evaluating hyperandrogenism.
1 citations
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October 2023 in “European journal of histochemistry” This study demonstrated that treating platelet-rich plasma with ozone or procaine in vitro led to distinct changes in platelet activity, significantly enhancing the release of platelet-derived factors without damaging the platelets, indicating potential for improved regenerative therapies.
July 2023 in “Endocrinology, diabetes & metabolism case reports” This case report involved a premenopausal woman with rapidly progressing virilizing symptoms caused by a rare sertoliform endometrioid carcinoma of the ovary. Following surgical intervention, her symptoms improved, highlighting the importance of recognizing virilizing symptoms as potential indicators of low-grade ovarian malignancies in similar cases.
22 citations
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January 1995 in “The American Journal of Medicine” This article reviews the negative effects of androgenic disorders and highlights that newer oral contraceptives with less androgenic progestins may reduce these effects and improve compliance, but it reports no new results.
In this study, researchers found that female rats exhibited more pronounced panic-related escape behavior during hypoxia, particularly in the diestrus phase, and that low-dose fluoxetine reduced this behavior, suggesting its potential for managing panic disorder symptoms related to hormonal cycles in women.
223 citations
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June 2018 in “Human Reproduction Update” This study concluded that including ovarian morphology in the diagnosis significantly increases the estimated prevalence of PCOS, revealing substantial variability due to clinical criteria and diagnostic cut-offs.
36 citations
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April 2017 in “journal of current ophthalmology” This review highlights essential preoperative assessments for ophthalmologists and non-oculo-facial surgeons performing upper facial rejuvenation, emphasizing the importance of understanding ocular and periocular anatomy to achieve both cosmetic and functional improvements.
September 2018 in “International journal of biosciences” This study found that women with both PCOS and gingivitis had significantly higher levels of AMH in their saliva compared to those with only PCOS, gingivitis, or neither condition.
2 citations
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July 2023 in “AACE Clinical Case Reports” In this case study, researchers identified a Leydig cell tumor in a 56-year-old postmenopausal woman with virilization symptoms by using ovarian vein sampling, as imaging was nonrevealing, and confirmed the tumor's location using testosterone ratios, which supported previous findings.
September 2023 in “Reproductive health of woman” This review examines the prevalence and symptoms of polycystic ovary syndrome (PCOS) across different ages, highlighting its varied dermatological and reproductive implications, but reports no new research findings.
3 citations
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April 2019 in “Journal of the Endocrine Society” This case report describes a rare instance of Satoyoshi syndrome in a 27-year-old Asian American woman, notable for her normal ovarian function despite typical syndrome features.
August 2022 in “Journal of Education Health and Sport” This article discusses the prevalence and impact of polycystic ovary syndrome on reproductive-aged women and reports no new clinical findings.
3 citations
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April 1991 in “PEDIATRICS” This reply argues that children with isolated extraordinary daytime frequency do not require extensive testing or aggressive pharmacologic treatments, noting potential negative effects of oxybutynin.
May 2006 in “Women's Health Medicine” This review examines the causes, assessment, and treatments of hirsutism and highlights the need for future research in managing this condition but presents no new research findings.
11 citations
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August 2019 in “PubMed” This review discusses the causes, evaluation, and treatment options for hirsutism in women, but reports no new clinical results.
12 citations
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May 2005 in “Current obstetrics and gynaecology/Current obstetrics & gynaecology” This review discusses the causes and treatment strategies for hirsutism, emphasizing that combination therapy targeting androgen suppression and hair removal techniques is most effective; no new clinical results are reported.
110 citations
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January 1984 in “Progress in brain research” This chapter reviews the potential role of gonadal hormones in sex differences in play and spatial behavior, noting a lack of conclusive evidence but suggesting perinatal androgen exposure might contribute to observed differences. It reports no new research results.
February 2026 in “Research Society and Development” This review highlights the multiple physical and psychological impacts of polycystic ovary syndrome in reproductive-aged women and underscores the importance of early medical evaluation and lifestyle changes for effective treatment.
January 2002 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study reported that 31.6% of female students experienced hirsutism, which was associated with menstrual abnormalities, acne, androgenic alopecia, hypertrichosis, and a familial history of hirsutism.
May 2023 in “Problems of Endocrinology” This study observed that "physiological" hyperandrogenism due to elevated total testosterone was associated with a 23.5% incidence of arterial hypertension, unlike hyperandrogenism due to elevated DHT levels.
12 citations
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March 2023 in “The FASEB Journal” This study found that platelet-rich plasma treatment significantly improved erectile function and restored neural structures in aged rats with erectile dysfunction, suggesting potential benefits for geriatric patients.
8 citations
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February 2010 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” This study developed a detailed classification system for functional androgenization in females that may enhance diagnosis and personalized treatment by identifying individual dysfunctions.