13 citations
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November 2012 in “PubMed” This study found that in men with sexual dysfunction, use of 5ARI may reduce sexual drive and spontaneous erections without worsening pre-existing erectile or ejaculatory issues.
July 2023 in “World Journal of Biology Pharmacy and Health Sciences” This research suggests that the drugs trazodone and chlorpromazine, which have effects on specific receptors, may help restore libido synaptic circuits and potentially treat sexual dysfunction associated with post-SSRI and post-finasteride syndromes.
June 2018 in “Evidence-Based Practice” This study found that patients using finasteride were up to twice as likely to experience sexual dysfunction, including ejaculation disorder, decreased libido, and impotence, compared to those not using the drug.
May 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This article evaluates clinical and scientific literature on post-finasteride syndrome, concluding that finasteride and dutasteride may cause persistent sexual, neurological, and physical adverse side effects in a subset of men.
33 citations
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January 2016 in “Skin appendage disorders” This review examines medical literature on postfinasteride syndrome and reports no new results; the authors call for more controlled studies on permanent sexual dysfunction and mood changes linked to 5-alpha-reductase inhibitors.
January 2016 in “The Korean Journal of Internal Medicine” This case report presents the first instance in Korea of unilateral gynecomastia and breast pain associated with doxazosin use.
44 citations
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July 2004 in “Archives of Dermatology” In this study, treatment with 1 mg of finasteride was associated with stable sexual function, suggesting that sexual side effects may be less common than indicated in clinical trials.
36 citations
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September 2001 in “Journal of The European Academy of Dermatology and Venereology” This study found that sexual and erectile function in men taking finasteride 1 mg did not significantly differ from age-matched controls, suggesting sexual side effects may be less common than previously reported.
19 citations
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November 2012 in “BJUI” In this study, researchers observed that the sexual effects of dihydrotestosterone deprivation using finasteride may vary by handedness, with right-handed men often experiencing lower sexual function and left-handed men showing no effect or improvement.
August 2016 in “Journal of Investigative Dermatology” This study found that Rosebay extract significantly reduced dandruff and sebum production, suggesting it may be an effective anti-dandruff ingredient as a complement or alternative to antifungal treatments.
August 2016 in “Journal of Investigative Dermatology” This study observed that the osteopontin-derived peptide FOL-005 inhibited hair growth in human scalp skin models, contrary to its hair growth promotion in mice, supporting further clinical testing for excessive hair growth treatment.
February 2018 in “The Journal of Sexual Medicine” In this animal study, finasteride exposure led to impaired spermatogenesis in rats, while the novel compound DA-9401, derived from three medicinal herbs, demonstrated potential in improving sperm parameters and reducing testicular apoptosis when used alone or with finasteride.
August 2016 in “Journal of Investigative Dermatology” This study observed that uncommon finasteride side effects included melasma, dry skin, tinnitus, postural hypotension, and oral lesions, with some symptoms persisting after treatment cessation.
August 2016 in “Journal of Investigative Dermatology” This study found that adverse effects of finasteride were more common among right-handed heterosexuals and left-handed homosexuals with androgenic alopecia.
August 2016 in “Journal of Investigative Dermatology” This study found that among men unresponsive to finasteride for androgenic alopecia, 56.25% showed significant hair improvement after six months of dutasteride treatment with reasonable adverse effects.
December 2023 in “Magna Scientia Advanced Research and Reviews” This study proposes that combining trazodone and clomiphene citrate could potentially restore libido synaptic circuits and treat post-finasteride syndrome, which involves persistent sexual dysfunction after discontinuing finasteride treatment.
13 citations
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August 2020 in “Der Hautarzt” This article discusses hyperandrogenism, including its symptoms, causes, and diagnostic approaches, and reports no new clinical results; it emphasizes the role of interdisciplinary care in treatment.
October 2023 in “Journal of the Endocrine Society” This observational study in Bogotá found that skin issues like acne and androgenetic alopecia are common among adults with gender dysphoria on hormone therapy, emphasizing the need for dermatological care as part of comprehensive treatment.
April 2024 in “Middle East Fertility Society Journal” In this study of infertile Indonesian women with PCOS, researchers found no correlation between hirsutism, body measurements, and sexual dysfunction scores, but noted that hirsutism may be linked to higher anxiety levels.
August 2021 in “Pelviperineology” This article discusses the complexity of vulvodynia and highlights the potential effectiveness of Fascial Manipulation therapy in addressing this condition, but it reports no new clinical results.
November 2025 in “Frontiers in Psychiatry” This study found that individuals with androgenetic alopecia experience significantly higher symptoms of anxiety, depression, and stress compared to controls, along with reduced self-esteem and life satisfaction, highlighting the importance of addressing psychological well-being in clinical treatments.
September 2021 in “Physiology News” This abstract provides template specifications for design materials but reports no new research findings.
20 citations
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August 2019 in “Expert Opinion on Drug Safety” This review examines the cognitive effects of medications for lower urinary tract symptoms and indicates that muscarinic antagonists, particularly oral oxybutynin, pose the highest risk for cognitive impairment.
40 citations
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February 2013 in “American Journal of Clinical Dermatology” This study found that people with androgenic alopecia, particularly women, are more prone to anxiety and depression, often adopting avoidant coping strategies, which are linked to emotional and psychological impacts rather than clinical severity.
February 2021 in “Facta Universitatis” This review discusses the current understanding of prolactin's role in female reproductive health and the diagnosis and treatment of hyperprolactinaemia but reports no new clinical findings.
8 citations
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January 2003 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study describes three female cases of androgen-dependent diseases in myotonic dystrophy, suggesting that peripheral androgen response, rather than serum levels, may drive such conditions.
12 citations
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May 2017 in “Journal of Dermatological Treatment” This study found that in adults over 25, stress from lifestyle changes, sensitive skin, stopping oral contraceptives, and the use of full-coverage foundations were associated with increased severity of acne.
January 2009 in “Side effects of drugs annual” This study observed no teratogenic effects of oral decongestants and surprisingly favorable neonatal outcomes in Swedish women who used them during pregnancy.
May 2025 in “Journal of the ASEAN Federation of Endocrine Societies” This case study reported a 68-year-old woman with postmenopausal virilization due to a rare Sertoli-Leydig cell tumor, where her symptoms and elevated testosterone levels only normalized post-surgery, underscoring the importance of thorough evaluation in such cases to improve diagnosis and treatment.
225 citations
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July 2007 in “The Journal of Sexual Medicine” In this study, patients informed about finasteride's potential sexual side effects reported a significantly higher occurrence of these side effects, suggesting a nocebo effect.