Postmenopausal Virilization

This case study highlights the importance of thorough evaluation in postmenopausal women presenting with virilization, as it may indicate rare ovarian tumors such as Sertoli-Leydig cell tumors. The report discusses a 68-year-old Indian woman who experienced worsening virilizing symptoms despite treatment, with persistently elevated testosterone levels. Imaging revealed an enlarged right ovary, and subsequent surgery confirmed a Sertoli-Leydig cell tumor. Post-surgery, her testosterone levels normalized, underscoring the need for increased awareness among clinicians to prevent diagnostic delays and improve patient quality of life.