Leydig Cell Tumor: A Rare Cause of Postmenopausal Hyperandrogenism

Leydig cell tumors, a rare cause of postmenopausal hyperandrogenism, can lead to symptoms like virilization and androgenic alopecia, as seen in a 62-year-old woman who experienced significant distress due to these changes. Despite initial misattribution to aging, further investigation revealed elevated testosterone levels and a Leydig cell tumor in the left ovary. Surgical removal of the tumor resulted in improved symptoms, including reduced hirsutism and hair loss, and normalized testosterone levels. This case highlights the importance of considering Leydig cell tumors in the differential diagnosis of postmenopausal hyperandrogenism and the need for thorough evaluation to alleviate patient distress.