Rebalance of the Scalp Microbiota by a Multifunctional Ingredient

August 2016 in “ Journal of Investigative Dermatology ”

Estelle Loing, J. Attia, Elisabeth Lamarque, M. Borel

dutasteride androgenic alopecia finasteride 5-alpha reductase hair density hair thickness Propecia Avodart

TLDR Dutasteride improved hair density and thickness in men not helped by finasteride, with minimal side effects.

In a 2016 study, researchers found that dutasteride was effective in treating men with androgenic alopecia who did not see improvements with finasteride. Out of 23 non-responders to finasteride, 16 were given dutasteride (0.5 mg/day) and after six months, 9 (56.25%) experienced significant improvements in hair density and thickness. Side effects were minimal, with only two patients experiencing transient erectile dysfunction and one patient having both erectile dysfunction and a slight depressive episode. The study suggested that dutasteride, which inhibits both type I and II 5-alpha reductase enzymes, could serve as an alternative treatment for androgenic alopecia, especially for those who do not benefit from finasteride.

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community COMPLETE OVERVIEW of the Treatment of androgenetic alopecia in men

26 upvotes 10 years ago

Male androgenetic alopecia is commonly treated with topical minoxidil and oral finasteride, both requiring continuous use. Other options include hair restoration surgery, dutasteride, light therapy, and camouflaging agents.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 673 upvotes 1 month ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Anyone else realize how many younger guys are balding?

in Chat 262 upvotes 1 month ago

Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

community Spironolactone for 11 years, finasteride for almost 5 years, started oral minoxidil in November 😢 ended oral contraceptive in Dec.

in Progress Pictures 224 upvotes 7 months ago

A user shared their 11-year experience with spironolactone and nearly 5 years with finasteride for hair loss, recently adding oral minoxidil and stopping birth control. Various treatments were discussed, including organic options, checking for underlying health issues, considering dutasteride, and the potential role of progesterone in hair loss.

community Effectiveness of Dutasteride opinions

in Finasteride/Dutasteride 11 upvotes 8 months ago

The conversation discusses the effectiveness of Dutasteride for hair loss, with some users reporting it works better than Finasteride and sharing positive experiences, while others are skeptical due to negative anecdotes. Specific treatments mentioned include Dutasteride and Finasteride.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.