TLDR Doxazosin may cause breast enlargement and pain in men.
Doxazosin, a commonly used alpha-adrenergic antagonist for benign prostatic hyperplasia, was reported in a case to cause unilateral gynecomastia and breast pain, marking the first such report in the country. While 5-alpha reductase inhibitors like finasteride and dutasteride frequently reported these side effects, alpha-adrenergic antagonists had not been associated with them domestically, and their pharmacological mechanism did not easily suggest such outcomes.
15 citations
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July 2016 in “Urologic Clinics of North America” Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.
2 citations
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January 2011 in “Clinical medicine insights” Dutasteride is effective for treating prostate enlargement and reducing related surgery risk, but is not approved for preventing prostate cancer.
1 citations
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December 2023 in “Curēus” Tadalafil is effective for treating urinary symptoms in men with BPH.
40 citations
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April 1999 in “Drugs” Finasteride treats enlarged prostate, improves urinary flow, but may cause sexual side effects.
67 citations
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February 2015 in “Life Sciences” Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.