A Case of Gynecomastia Induced by Use of Doxazosin

    March 2016 in “ Korean Journal of Medicine
    In Seong Park, Nam Hee Yi, Chi Hwan Park, Seung Woon Park, Jin Yu, Joon Hoon Jeong
    TLDR Doxazosin can cause male breast growth and milk production.
    The document described a case of gynecomastia, a condition characterized by the development of breast tissue in males, which was induced by the use of doxazosin. Doxazosin is typically used as an alpha-adrenergic blocker for treating conditions like hypertension and benign prostatic hyperplasia. The case was notable as it was the first reported instance in the country where doxazosin led to the development of gynecomastia and galactorrhea, which is the production of breast milk. This case highlighted the potential for doxazosin to cause unexpected side effects similar to those seen with other medications like finasteride and dutasteride, which are known to affect hormonal pathways.
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