6 citations,
June 1976 in “Journal of ultrastructure research” Keratinized wool cells still have some organelles like lysosomes and mitochondria.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Primary cilia affect the size and oil production of eye glands but not the oil's makeup.
5 citations,
March 2017 in “Molecular biology of the cell” Different parts of cells interact at specific areas to control cell functions like energy production and fat storage.
February 2022 in “Cosmetic Dermatology” Platelet Rich Plasma (PRP) is increasingly used in cosmetic dermatology for hair loss, facial rejuvenation, and after cosmetic procedures, and can be stored for up to 90 days for daily home use.
1 citations,
April 2016 in “Journal of lipid research” Lipin-1 is important for skin cell differentiation and skin barrier function.
Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.
April 2023 in “Journal of Investigative Dermatology” Mitochondrial dysfunction contributes to skin aging and hair loss.
93 citations,
October 2006 in “The International Journal of Biochemistry & Cell Biology” Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.
2 citations,
July 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Autophagy changes the protein makeup of hair.
60 citations,
July 2014 in “Autophagy” The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
April 1986 in “CRC Press eBooks” Hair color is determined by melanins produced in hair cells.
11 citations,
January 1977 in “Archives of dermatological research” Mouse tail skin has different keratinization near hair follicles and scales.
375 citations,
June 2013 in “Biochimica et biophysica acta. Molecular cell research” Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
26 citations,
December 2020 in “Nature metabolism” Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
February 2005 in “CRC Press eBooks” Hair color is due to active pigment cells in hair during growth.
130 citations,
August 2020 in “Drug Design Development and Therapy” Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
7 citations,
January 2023 in “Journal of Hematology & Oncology” Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
October 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Neuronatin is found in various cells of rat tissues and has a unique location in sperm cells.
152 citations,
December 2003 in “Micron” As people age, their hair follicles produce less pigment, leading to gray and white hair, due to factors like reduced enzyme activity and damage to melanocyte DNA.
November 2005 in “Physiology” Apoptosis, not oxidative stress, is linked to aging in mice with mtDNA mutations.
12 citations,
July 2013 in “Circulation” Improving mitochondrial health may better treat atherosclerosis than antioxidants.
16 citations,
November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Hair color is determined by different melanins and changes with age.
1 citations,
November 2013 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Experts met to improve care for ichthyosis patients in Spain.
April 2018 in “Journal of Investigative Dermatology” Minoxidil didn't significantly increase hair growth in minipigs.
37 citations,
October 2017 in “Advanced drug delivery reviews” The review suggests that there are various treatments to help restore skin color after severe burns.
March 2024 in “International journal of molecular sciences” Mitochondrial dysfunction is linked to various skin conditions and could be a target for treatments.
June 2023 in “Journal of cosmetic medicine” Hair follicle stem cells and mitochondria are key for hair growth, and targeting their activity could lead to new hair loss treatments.
146 citations,
May 2002 in “The American journal of pathology” Cathepsin L is essential for normal hair growth and development.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” HSD11b1 affects skin nerves and increases non-histaminergic itch.
11 citations,
February 2003 in “Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology” Acne and increased body hair in teenage girls are normal but severe cases may need hormone evaluation and treatment can prevent diabetes linked to PCO.