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GlossaryMelanosomes

specialized organelles that produce and store melanin pigment

Melanosomes are specialized organelles within cells called melanocytes that produce and store melanin, the pigment responsible for the color of skin, hair, and eyes. These organelles play a crucial role in protecting the skin from UV radiation by absorbing and dissipating harmful rays.

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research Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle

31 citations, November 2015 in “PloS one”

Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.

research The Distribution of Melanocytes and the Degradation of Melanosomes in Fetal Hair Follicles

4 citations, January 2019 in “Micron”

Fetal hair follicles have melanocytes with melanosomes at different stages, which are broken down into pigment particles in keratinocytes.

research Dynein Is Involved in the Movement, Distribution, Acidity, and Transfer of Melanosomes

November 2022 in “Journal of Investigative Dermatology”

Dynlt3 is important for melanosome transport and skin coloration.

research Observation of Cultured Amelanotic Melanocytes from Hair Follicles by Atomic Force Microscopy

January 2006 in “Chinese Journal of Dermatology”

Amelanotic melanocytes from hair follicles are immature and likely don't transfer melanosomes to keratinocytes.

research Melanocytes: The New Black

93 citations, October 2006 in “The International Journal of Biochemistry & Cell Biology”

Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.

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