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GlossaryMelanosomes

specialized organelles that produce and store melanin pigment

Melanosomes are specialized organelles within cells called melanocytes that produce and store melanin, the pigment responsible for the color of skin, hair, and eyes. These organelles play a crucial role in protecting the skin from UV radiation by absorbing and dissipating harmful rays.

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research Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle

31 citations , November 2015 in “PloS one”

Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.

research Effects of Aging on Hair Color, Melanosomes, and Melanin Composition in Japanese Males and Their Sex Differences

7 citations , November 2022 in “International Journal of Molecular Sciences”

As Japanese males age, their hair darkens due to increased melanin, with males generally having darker hair than females.

research Dynein Is Involved in the Movement, Distribution, Acidity, and Transfer of Melanosomes

November 2022 in “Journal of Investigative Dermatology”

Dynlt3 is important for melanosome transport and skin coloration.

research Observation of Cultured Amelanotic Melanocytes from Hair Follicles by Atomic Force Microscopy

January 2006 in “Chinese Journal of Dermatology”

Amelanotic melanocytes from hair follicles are immature and likely don't transfer melanosomes to keratinocytes.

research Human Hair Melanins: What We Have Learned and Have Not Learned from Mouse Coat Color Pigmentation

140 citations , August 2010 in “Pigment Cell & Melanoma Research”

We know a lot about mouse hair color, but not much about human hair color differences.

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