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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Human skin can make serotonin and melatonin.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Noggin is necessary to start the hair growth phase in skin after birth.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Androgens can both increase and decrease hair growth in different parts of the body.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Telocytes might help with skin repair and regeneration.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Minoxidil boosts hair growth by increasing cell production and survival.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Different types of stem cells and their environments are key to skin repair and maintenance.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.