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The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Different types of stem cells and their environments are key to skin repair and maintenance.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

Foals with Rhodococcus equi infection often have other health problems that lower their chances of survival.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.

Voriconazole can cause serious side effects, especially in long-term use.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.

New antifungal treatments for a children's scalp infection are effective and safe, but it's not decided if they will become the preferred option over the old treatment.

Alopecia Areata is an autoimmune condition often starting before age 20, with varied treatment success and a need for personalized treatment plans.

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Follistatin helps hair growth and cycling, while activin prevents it.

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.

Hair grays due to oxidative stress and fewer functioning melanocytes.