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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

The virus was not found in the semen and urine of a man who tested positive for COVID-19.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

High androgen levels in young women with PCOS are linked to higher blood pressure.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Finasteride may help some male chronic pelvic pain patients, but more research needed.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.

Plant cell culture is a promising method for creating sustainable and high-quality cosmetic ingredients.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Human hair follicles can make and process prostaglandins, which may affect hair growth.