47 citations
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September 2023 in “Pharmacological Reports” In this review, researchers explored the roles of vitamins A, B3, C, D, and E in skin immunity, highlighting their potential as therapeutics for skin diseases due to their antioxidant, anti-inflammatory, and antimicrobial properties.
47 citations
,
December 2020 in “Journal of the European Academy of Dermatology and Venereology” This article reviews the classification, diagnosis, and management of hair disorders, emphasizing the role of trichoscopy and early diagnosis for effective treatment but reports no new clinical findings.
41 citations
,
January 2020 in “BioMed Research International” This study found that micrografts containing human hair follicle mesenchymal stem cells significantly increased hair count and density compared to placebo over 58 weeks in patients experiencing hair loss.
40 citations
,
February 2020 in “Experimental and Therapeutic Medicine” This study found that autologous serum platelet-rich plasma improved skin quality and reduced wrinkles, texture, and pores in healthy females, partly by regulating the expression of MMP-1, tyrosinase, fibrillin, and tropoelastin.
39 citations
,
March 2019 in “Dermatologic Surgery” This study's meta-analysis reported that PRP injections significantly increased hair density compared to baseline and placebo in androgenetic alopecia patients, supporting its use as a beneficial treatment.
33 citations
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November 2019 in “Journal of Controlled Release” In this study, researchers developed a new self-administered finasteride delivery system using powder-carrying microneedles that improved hair growth efficacy and addressed safety concerns compared to topical finasteride gel by allowing sustained intradermal release of the drug for three days with a single application.
31 citations
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January 2019 in “Journal of Cutaneous Medicine and Surgery” This review found that three monthly PRP injections improved hair density in patients with androgenetic alopecia compared to placebo, but more rigorous studies are needed for broader dermatological applications.
29 citations
,
September 2020 in “International Journal of Molecular Sciences” This review outlines the current state of freeze-dried platelet-rich plasma (FD-PRP) research, emphasizing its use in wound healing, lumbar fusion, knee conditions, and dentistry, but reports no new clinical findings.
27 citations
,
January 2020 in “Experimental Dermatology” This review discusses the role of immune cells in mammalian hair cycle control and highlights their potential relevance to human hair cycling disorders, reporting no new clinical findings.
26 citations
,
April 2019 in “Journal of Cosmetic Dermatology” This review discusses the potential of herbal treatments like Saw palmetto, Green tea, and Rosemary as alternatives to conventional drugs for androgenetic alopecia, noting that these herbs may inhibit the 5-alpha-reductase enzyme and reduce hair loss with fewer side effects.
26 citations
,
May 2017 in “Lasers in Medical Science” This study found that combining ablative fractional CO₂ laser therapy with hair growth factors significantly increased hair density in men with androgenetic alopecia compared to using growth factors alone.
21 citations
,
June 2019 in “Dermatologic Surgery” This research review found that platelet-rich plasma treatment generally produced successful hair regrowth in both androgenetic alopecia and alopecia areata, despite study differences that limited direct statistical comparison.
20 citations
,
January 2018 in “Expert Opinion on Drug Safety” This review discusses androgenetic alopecia management with 5α-reductase inhibitors, emphasizing that while dutasteride shows superior efficacy, finasteride is suggested as preferable due to predictable adverse effects and preservation of physiological roles.
19 citations
,
October 2019 in “Dermatology Practical & Conceptual” This review discusses the expanding applications of dermoscopy in dermatological diagnosis beyond its initial use for detecting dysplastic nevi and reports no new clinical results.
18 citations
,
August 2019 in “Journal of Cosmetic Dermatology” This study found that autologous platelet-rich plasma was associated with increased hair density in people with pattern hair loss, but with considerable variability and unclear risks of bias.
17 citations
,
January 2021 in “Dermatology and Therapy” This review discusses laser-assisted drug delivery for enhancing topical treatment efficacy in various dermatological and medical applications but reports no new clinical results, emphasizing the need for further research to optimize its use.
16 citations
,
July 2018 in “Dermatologic Surgery” In this study, iL-PRF injections produced significantly better clinical scores for androgenetic alopecia patients compared to controls, especially in those with more severe baseline conditions.
15 citations
,
May 2020 in “Journal of Dermatological Treatment” This systematic review and meta-analysis found that platelet-rich plasma treatments improved hair density and thickness in people with androgenetic alopecia, without serious adverse effects.
15 citations
,
September 2017 in “Dermatologic Surgery” This literature review found that chemical peels are effective for treating various skin conditions in men, such as acne, rosacea, and photodamage, and noted that men may require more treatments or stronger peels due to their skin's characteristics.
13 citations
,
January 2024 in “Cureus” This study reviewed the physiological and psychological impacts of acne vulgaris, highlighting its complex interactions with endocrine issues, sebum production, and immune response, while suggesting that a multidisciplinary approach can inform future treatments and improve quality of life for those affected.
13 citations
,
September 2020 in “International Journal of Molecular Sciences” This study found that combining platelet-rich plasma therapy with minoxidil was more effective in treating androgenetic alopecia in men than either treatment alone.
13 citations
,
May 2020 in “Journal of Plastic Reconstructive and Aesthetic Surgery” This systematic review found inconclusive evidence on the effectiveness of botulinum toxin for treating alopecia and highlighted the need for further prospective randomized controlled trials.
12 citations
,
June 2020 in “Dermatology and therapy” This article reviews major uses of platelet-rich plasma in treating various hair disorders, including both non-cicatricial and cicatricial alopecia, but reports no new results.
12 citations
,
May 2019 in “Aesthetic Surgery Journal” This review highlights new treatment options for hair restoration, including platelet-rich plasma and stem cell therapy, which have shown efficacy in increasing hair count and density for androgenetic alopecia and alopecia areata, but presents no original clinical data.
12 citations
,
June 2018 in “Journal of Cosmetic Dermatology” This review outlines recent research on platelet-rich plasma, alone or combined with other therapies, for managing hair loss disorders, and discusses future prospects without reporting new clinical findings.
11 citations
,
May 2021 in “Journal of Cosmetic Dermatology” This review discusses the potential use of platelet-rich plasma for treating melasma, suggesting its effectiveness but noting the need for more extensive studies to confirm these findings.
11 citations
,
May 2021 in “Dermatologic clinics” This review discusses platelet-rich plasma and cell-based therapies for hair loss, noting promising results but emphasizing the need for standardization and robust trials to confirm their efficacy.
11 citations
,
August 2020 in “Dermatologic therapy” This review article highlights that mesotherapy, a popular non-surgical procedure in aesthetic dermatology, involves injecting a mixture of compounds into the skin for purposes like skin rejuvenation and hair loss treatment, but lacks large-scale studies on its efficacy and safety.
11 citations
,
July 2017 in “Expert Opinion on Investigational Drugs” This review discusses current and emerging therapeutic strategies for androgenetic alopecia, noting limited evidence but suggesting areas such as prostaglandin analogs, PRP, and progenitor cell therapies as promising future directions.
8 citations
,
February 2020 in “Aesthetic Surgery Journal” This study found that early male hair loss treatment with Puregraft fat and low-dose adipose-derived regenerative cells increased terminal hair counts at 24 weeks compared to a saline control, indicating promise for androgenetic alopecia treatment.