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Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Hair follicle stem cells can turn into various cell types and help repair nerves.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

Potassium channel openers like minoxidil help hair grow by acting on hair follicles.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

Too much thymosin beta4 causes weird teeth and more hair growth in mice.

Hair follicle stem cells are a practical and ethical option for nerve repair in regenerative medicine.

Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

The article concludes that the global hair trade is exploitative and reflects complex cultural and economic issues.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

The combination therapy improved PCOS symptoms in both obese and non-obese women, with weight loss in the obese group.

The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.

The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.

Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.

Castration and finasteride lower urinary oxalate in male rats, potentially treating urolithiasis.