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Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

New cancer treatments show promise in reducing tumor growth and improving skin regeneration in mice.

The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.

Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.

Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.

Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.

Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.

New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.

Atorvastatin reversed memory problems caused by cancer drug trastuzumab and improved its cancer-fighting abilities without causing hair loss.

L-cystine and vitamin B6 at high doses prevented hair loss in mice treated with a chemotherapy drug.

Finasteride may cause kidney damage.

Green tea extract helps prevent cell death and supports cell survival in hair cells exposed to a chemotherapy drug.

Human hair follicle cells can be turned into stem cells that may help clone hair for treating hair loss or burns.

Polyomavirus A2 infection in newborn mice caused hair follicle tumors.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Platelet-rich plasma may help hair follicle cells grow by affecting certain genes and pathways.

Activin A is important for creating new hair follicles.

Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

XIST RNA helps regenerate hair follicles by targeting miR-424 and activating hedgehog signaling.

Mycophenolate helps reverse hair loss effects caused by IFN-γ by activating a key hair growth pathway.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Herbal extracts and platelet-rich plasma together may help increase hair growth by making certain cells grow more, through specific cell growth pathways.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

Applying EGCG on the skin can prevent hair loss caused by testosterone in mice.

sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.

TGF-alpha is present in sheep and ferret skin and may affect hair growth without directly stimulating cell proliferation.