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690-720 / 1000+ resultsresearch Additional file 1 of Rejuvenating senescent hair follicles: a novel conjugated linoleic acid based nanovesicle approach to treat androgenic alopecia
research Therapeutic potential of Ishophloroglucin a from Ishige okamurae in androgenic alopecia: inhibition of 5α-reductase activity and activation of the Wnt/β-catenin signaling pathway in human dermal papilla cells
This study found that Ishophloroglucin A from brown seaweed may treat androgenic alopecia by inhibiting 5α-reductase and promoting hair growth-related factors in human dermal papilla cells.
research Activation of temperature-sensitive Ca2+-permeable TRPV3 channels by natural ï¡-hydroxyl acids causes exfoliation for skin-resurfacing
This presentation suggests that the activation of TRPV3 channels by fruit acids and carvacrol contributes to exfoliation and may underlie the skin-resurfacing effects of chemical peels.
research Immunomodulatory Potential of a Bibenzyl-dihydrophenanthrene Derivative Isolated from Calanthe cardioglossa
In this study, researchers isolated new compounds from the plant *Calanthe cardioglossa* and found that five of these compounds, particularly calancardin B, significantly reduced TNF-α levels in immune cells relevant to multiple sclerosis, suggesting potential for immunomodulatory effects.
research Substantiation of technological parameters of the oil extract obtained from Urtica dioica roots based on the yield determination of phytosterols using capillary gas chromatography method
This study identified optimal parameters for extracting oil from Urtica dioica roots to maximize phytosterol content, using corn oil and a 1:5 raw material-extract ratio over a 6-hour maceration period.
research Relationships between hair-follicle afferent axons and glycine-immunoreactive profiles in cat spinal dorsal horn
Aδ-LTMRs have complex synapses with glycine, while Aβ-LTMRs have simpler ones.
research UHPLC/Q-TOFMS-based plasma metabolomics of polycystic ovary syndrome patients with and without insulin resistance
This study identified trilauric glyceride and decanoylcarnitine as potential biomarkers for diagnosing PCOS in patients with and without insulin resistance, suggesting significant metabolic alterations in these conditions.
research Genetically determined metabolites in allergic conjunctivitis: A Mendelian randomization study
This study found a causal link between eight blood metabolites and allergic conjunctivitis, highlighting their potential role in predicting and preventing the condition.
research Activation of Hair Cell Growth Factors by Linoleic Acid in Malva verticillata Seed
This study found that linoleic acid from Malva verticillata seed extracts may promote hair follicle cell growth and counteract hair loss signaling in a lab setting.
research Four hypotrichosis families with mutations in the gene LSS presenting with and without neurodevelopmental phenotypes
This study identified novel LSS mutations implicated in hypotrichosis simplex with or without neurodevelopmental abnormalities, highlighting the need for careful evaluation of synonymous mutations' potential pathogenic effects.
research Lipid Profile and 5α-Reductase Inhibition Activity of Proprietary Ultrahigh-Pressure Supercritical Carbon Dioxide and Hexane Saw Palmetto Extracts
This study found that both a proprietary ultrahigh-pressure extract and a hexanic extract of saw palmetto showed comparable inhibition of 5α-reductase, suggesting similar potential for managing symptoms of benign prostatic hyperplasia.
research Topical tacalcitol ointment can be a good therapeutic choice in erythromelanosis follicularis faciei et colli
This study found that topical tacalcitol improved roughness and scaling in erythromelanosis follicularis faciei et colli, although it was less effective for facial erythema.
research Identification and in-silico analysis of phytochemicals from Phyla nodiflora (L.): Potential bioactive compounds for therapeutic applications
This study investigated the therapeutic potential of phytochemicals from Phyla nodiflora, identifying 50 bioactive compounds through GC-MS analysis. Among them, n-hexadecanoic acid, stigmasterol, and beta-sitosterol showed promise in molecular docking studies as drug candidates for diabetes, alopecia, cancer, and anti-diuresis.
research Efficacy and safety of Latilactobacillus curvatus LB-P9 on hair health: a randomized, double-blind, placebo-controlled clinical trial
In this randomized controlled trial, oral intake of the probiotic Latilactobacillus curvatus LB-P9 significantly improved hair luster, elasticity, and participant satisfaction in individuals with mild to moderate hair damage compared to placebo, without significant adverse effects reported.
research Malus pumila Mill. cv Annurca apple extract might be therapeutically useful against oxidative stress and patterned hair loss
In this study, testing Annurca apple extract on human follicle dermal papilla cells indicated its potential to prevent patterned hair loss by reducing oxidative stress and increasing factors involved in hair growth.
research LPA3, a unique G protein-coupled receptor for lysophosphatidic acid
This review discusses the role of LPA(3) in embryo implantation and its genetic connection with prostaglandin signaling, but reports no new clinical results.
research Valproic acid – induced Pleuro-pericardial Effusion
This case report details a 66-year-old male patient who developed eosinophilic pleuro-pericardial effusion likely due to valproic acid toxicity or overdosage, with full recovery observed after medication adjustments at a six-month follow-up.
research Antioxidant and Anticancer Activities of Anethum graveolens L., Citrus limon (L.) Osbeck and Zingiber officinale Roscoe Essential Oils
This study observed that Citrus limon essential oil demonstrated significant anticancer activity against an MCF-7 breast cancer cell line, suggesting its potential as a complementary cancer treatment.
research Unique amino acid signatures that are evolutionarily conserved distinguish simple-type, epidermal and hair keratins
This study found that keratins have evolutionarily conserved and domain-selectively enriched amino acids, which likely reflect their unique structural roles, with distinct patterns observed among epidermal, hair, and simple-type epithelial keratins.
research 오리나무 가지 유래 Oregonin의 인체 모유두 세포 Apoptosis 조절 효능
This study found that oregonin isolated from Alnus japonica exhibits strong antioxidant activity and may promote hair growth, suggesting its potential use in cosmetic products.
research Lipolytic agents for submental fat reduction: Review
This study reviewed various lipolytic agents for reducing submental fat and highlighted that while deoxycholic acid is FDA-approved, other compounds like phosphatidylcholine with deoxycholate lack cosmetic approval due to safety concerns. Understanding these agents' mechanisms and anatomy is crucial for safe fat reduction applications.
research 未利用資源の乳酸菌発酵による高付加価値化と化粧品原料への応用
Lactic acid bacteria fermentation can turn waste into valuable skincare ingredients.
research Active pharmaceutical ingredient-ionic liquids assisted follicular co-delivery of ferulic acid and finasteride for enhancing targeted anti-alopecia
This study reported that a novel ionic liquid delivery system combining ferulic acid and finasteride enhanced the solubility, skin permeation, and effectiveness in promoting hair regrowth in androgenetic alopecia mice, suggesting an improved topical treatment approach.
research Effect of Optimal Mixing Ratio of Dendropanax, Sea Salt, and Other Extracts on the Alleviation of Hair Loss Symptoms
This study reported that a specific mixing ratio of Dendropanax extract and sea salt showed low cytotoxicity, high cell proliferation, anti-inflammatory, and antimicrobial effects, suggesting potential for functional cosmetics against hair loss.
research Crystal Structure of 17-.BETA.-Benzoyloxy-16-.BETA.-methylpregna-4,6-diene-3,20-dione.
A new antiandrogen compound was made and its detailed three-dimensional shape was described.
research Homozygous ALOXE3 Nonsense Variant Identified in a Patient with Non-Bullous Congenital Ichthyosiform Erythroderma Complicated by Superimposed Bullous Majocchi’s Granuloma: The Consequences of Skin Barrier Dysfunction
In this study, a genetic analysis identified a pathogenic variant in the ALOXE3 gene associated with non-bullous congenital ichthyosiform erythroderma, and the patient's response to antifungal treatment highlights the risk of cutaneous fungal infections.
research Study on hair root lipids of female androgenetic alopecia based on UPLC‐Q‐TOF / MS results
This letter to the editor reports on an analysis of hair root lipids in female androgenetic alopecia using UPLC-Q-TOF/MS, without presenting new clinical results.
research Hair growth promoting effect of essence manufactured with products fermented by Lactobacillus rhamnosus and Backryeoncho (Opuntia ficus-indica var. sarboten) fruits in mice
This study found that essence containing fermented Opuntia ficus-indica var. sarboten fruits and Lactobacillus rhamnosus promoted more significant hair growth in mice than minoxidil.
research Investigation of the chemical composition of phenolic compounds in Equisetum arvense (L.) extracts of water and ethanol
This study aimed to determine the phenolic compound composition in Equisetum arvense stem extracts using HPLC, as the plant is commonly used in cosmetics for skin and hair care, but results are not reported here.