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Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.

Understanding hair biology is key to developing better treatments for hair and scalp issues.

Girls with PCOS have higher levels of certain androgens, which are linked to excess hair growth, but these androgens don't help diagnose PCOS.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Testosterone is linked to cardiovascular risk factors and stroke, but its exact role is unclear.

Early hair loss may indicate future prostate issues.

Dermatologists play a key role in identifying and documenting signs of abuse and injury for forensic investigations.

5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.

Vismodegib is effective for basal cell carcinoma but has severe side effects.

A 24-month-old Nigerian girl developed early puberty with no family history, needing treatment her family couldn't afford.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.

DA-9401 helps protect rat testis from finasteride damage.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

No treatment has been proven to effectively stop hair loss or regrow hair in Frontal Fibrosing Alopecia, and more research is needed.

New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Early NAS level changes affect alcohol consumption vulnerability.

Many women with polycystic ovary syndrome have normal blood sugar, but some may have higher blood sugar levels or diabetes, especially if they are older, overweight, and have certain hormone levels.

Millets may help reduce chemotherapy side effects like nausea, fatigue, and hair loss.

Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.

Tadalafil is effective for treating urinary symptoms in men with BPH.

Propylene glycol and ethanol increase finasteride skin absorption, sodium lauryl sulfate doesn't.

Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Eating a Mediterranean diet and taking certain supplements may improve symptoms of PCOS.

Microemulsions could improve skin drug delivery but face challenges like complex creation and potential toxicity.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

Testosterone's effects on COVID-19 are unclear and need more research.