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60-90 / 1000+ resultsresearch UTILIZAÇÃO DOS FIOS ABSORVÍVEIS DE POLIDIOXANONA NO REJUVENESCIMENTO FACIAL
This article reviews the use of polydioxanone (PDO) threads for facial rejuvenation and reports no new clinical findings, highlighting their safety and potential for natural, durable results.
research Evaluation of the safety and effectiveness of intradermal administration of QR678 Neo® hair growth factor formulation: A phase‐IV, open‐label, single‐arm multi‐ethnicity clinical trial
This study found that intradermal administration of QR678 Neo® significantly reduced hair fall and improved hair growth in patients with androgenetic alopecia and female pattern hair loss, with no side effects reported during long-term follow-up.
research 15-Hydroxyprostaglandin Dehydrogenase Inhibitor Restores Endothelial Function Under Dihydrotestosterone-Induced Stress in Human Dermal Microvascular Endothelial Cells
This study found that the 15-PGDH inhibitor DPP improved endothelial function in hair-related cells exposed to DHT by reducing oxidative stress and enhancing angiogenic capacity.
research 50579 Novel Cosmetic Formulation Rapidly Reduces Hair Shedding
In this prospective, placebo-controlled study, the researchers observed a significant reduction in hair shedding in women after applying the combined topical treatment DA-OTC-002, containing synephrine and TAAR agonists, compared to placebo, showing a 62.5% average reduction with no reported adverse events.
research QR 678 & QR678 Neo Vs PRP—A randomised, comparative, prospective study
In this study, intradermal injections of QR678 were found to significantly reduce hair fall in men with androgenetic alopecia over 6 months, with superior improvements in hair density and thickness compared to PRP.
research P46 PSYCHOMETRIC PERFORMANCE OF EQ-5D-5L INDEX IN ADULTS AND ADOLESCENTS WITH SEVERE ALOPECIA AREATA: EVIDENCE FROM PHASE III TRIAL DATA
research 50804 Low-Dose Oral Minoxidil Initiation and Monitoring (LOMI) For Hair Loss: A Modified Delphi Consensus of Experts
This review discusses the consensus reached by international experts on guidelines for prescribing and monitoring low-dose oral minoxidil for hair loss, and reports no new clinical results.
research SnapshotDx Quiz: May 2022
This paper presents an interactive quiz related to a study by Deng et al. (2022) in the Journal of Investigative Dermatology, examining androgen receptor-mediated paracrine signaling in androgenetic alopecia, but it provides no new clinical findings.
research AAD 2024 Interview: Yagiz Matthew Akiska
This study developed expert consensus guidelines on the safe and effective prescription of low-dose oral minoxidil for treating hair loss by engaging 43 dermatologists from 12 countries in a structured Delphi process, yielding 78 consensus items on safety, efficacy, dosing, and monitoring.
research O-T-C Hair Preparations
research Pegylated Liposomal Doxorubicin: Metamorphosis of an Old Drug into a New Form of Chemotherapy
This review describes the unique pharmacological profile and clinical applications of pegylated liposomal doxorubicin, emphasizing its role in Kaposi's sarcoma and recurrent ovarian cancer, but reports no new clinical results.
research Genetic association of HLA‐DQB1 and HLA‐DRB1 polymorphisms with alopecia areata in the Italian population
This study found that in an Italian population, the HLA-DQB1*03 allele was associated with increased susceptibility to alopecia areata, particularly in cases with more than 50% hair loss.
research Dimensions of drug information
This study introduced a pre-formal ontology matching approach using 39 identified dimensions to integrate drug information, improving database normalization and supporting complex use cases.
research The Polycystic Ovary Syndrome Health-Related Quality-of-Life Questionnaire: Confirmatory Factor Analysis
This study found that the revised 43-item PCOSQ had better validity and reliability than the original version, although further studies are needed to assess its predictive efficacy.
research Polydioxanone threads in androgenetic alopecia: A novel innovation
In this study, polydioxanone threads significantly reduced hair loss and promoted hair regrowth in patients with androgenetic alopecia who did not respond to minoxidil and finasteride.
research Responsiveness of the DLQI and the Colombian validated version of the Skindex-29 in scarring and non-scarring alopecia
In this study, researchers assessed the quality of life in patients with different types of alopecia using the Skindex-29 and DLQI questionnaires, finding that telogen effluvium and alopecia areata had the greatest pretreatment impact on quality of life, with moderate responsiveness observed after treatment.
research Development of the First Health-Related Quality of Life Questionnaires in Arabic for Women with Polycystic Ovary Syndrome (Part I): The Creation and Reliability Analysis of PCOSQoL-47 and PCOSQoL-42 Questionnaires
This study developed two highly reliable Arabic HRQoL questionnaires for evaluating quality of life in married and unmarried women with polycystic ovary syndrome.
research Change in Hair Cycle and Hair Length in Nude Mice by Administration of Deuterium Oxide
This study suggests that D2O increases hair length in nude mice by extending the hair cycle duration, particularly the hair-existing phase, which is associated with increased mast cell density.
research Bioinspired multifunctional injectable hydrogel for hemostasis and infected wound management
This study reported that a new bioinspired injectable hydrogel, CQCS@gel, showed promise as a multifunctional wound dressing by achieving rapid hemostasis and promoting the healing of infected skin wounds in both in vitro and in vivo tests.
research Fe-MOF@Quercetin Complex with Light-controlled Redox Modulation for Tumor Wound Repair
This study demonstrated that in a mouse melanoma wound model, the MQ Microneedles effectively managed ROS levels to inhibit tumor growth and promote wound healing through light-controlled release.
research Carbon quantum dots applied to the chemical sensing of cobalt ions and methylcobalamin
This study found that Carbon Quantum Dots effectively detected and quantified Co²⁺ ions and methylcobalamin in tap water with high sensitivity and recovery rates between 95% and 105%.
research Dendrobium officinale polysaccharide improves hair regrowth in androgenetic alopecia mice and is associated with coordinated changes in local steroid metabolism, ESR1 activation, and keratin-related follicular responses
In this study, DOP treatment improved hair regrowth in androgenetic alopecia by altering local steroid metabolism and follicular morphology.
research Gain‐of‐function variants in the ODC1 gene cause a syndromic neurodevelopmental disorder associated with macrocephaly, alopecia, dysmorphic features, and neuroimaging abnormalities
This report describes a neurometabolic disorder linked to gain-of-function variants in the ODC1 gene, characterized by developmental delay, ectodermal abnormalities, and notable facial and neuroimaging features.
research Heterogeneity of ornithine decarboxylase expression in 12-O-tetradecanoylphorbol-13-acetate-treated mouse skin and in epidermal tumors
This study found that TPA treatment transiently induces high levels of ODC in mouse epidermal cells, particularly around hair follicles, with localization reduced by retinoic acid or cycloheximide pretreatment.
research A Novel and Safe Modality for Non-Surgical Hair Restoration using Polydioxanone Monofilament Threads
In this study, 10 men with androgenetic alopecia who did not respond to standard treatments showed significant hair regrowth and satisfaction after being treated with polydioxanone scalp threads, suggesting a potential therapeutic advantage for this approach.
research Development of a health-related quality of life questionnaire for women with androgenetic alopecia
This study developed the Women's Androgenetic Alopecia Quality of Life Questionnaire, which shows high reliability and internal consistency for assessing the impact of AGA on women's quality of life.
research Correction of Diffuse Alopecia in Iron Deficiency Anemia
In this study, researchers explored the causes and treatment strategies for diffuse telogen effluvium, focusing on 60 patients with the condition linked to iron deficiency anemia, comparing the effectiveness of ferrous salts alone versus combined with Quilib lotion.
research Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/– mice
In this study, overexpression of ornithine decarboxylase accelerated basal cell carcinoma in Ptch1+/– mice under UVB exposure, while its inhibition reduced tumor induction, suggesting potential chemoprevention strategies in humans.
research Tumor suppressor activity of ODC antizyme in MEK-driven skin tumorigenesis
In this study, crossing mice overexpressing antizyme with MEK mutants significantly delayed tumor development and reduced tumor frequency, likely by slowing cell growth in skin tumors.