research Increased Androgen Receptor Messenger RNA in Frontal-Parietal Hair Follicles of Women with Androgenetic Alopecia
Women with hair loss have more androgen receptors in certain hair follicles.
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30-60 / 1000+ results research Increased Expression of Zyxin and Its Potential Function in Androgenetic Alopecia
Inhibiting Zyxin may help treat androgenetic alopecia by promoting hair growth.
research Accelerated Aging of Hair Follicles in Androgenetic Alopecia
Hair follicles in androgenetic alopecia age faster, especially in the front.
research Mechanism of Action of Androgen in Hair Follicles
Testosterone affects hair follicles differently across body sites, with beard hair follicles showing more activity of a specific enzyme and presence of androgen receptors compared to scalp hair.
research Guidelines on Hair Restoration for East Asian Patients
Hair restoration for East Asians should consider their unique characteristics like head shape, hair thickness, and hair density, and use modified procedures and treatments to minimize scarring and maintain hair density.
research Effects of Hormones and Endocrine Disorders on Hair Growth
Hormones significantly influence hair growth, with conditions like hirsutism and patterned hair loss linked to hormone levels; more research is needed for full understanding.
research Changing Faces: Can a New Identity Stop Balding?
Changing hair follicle identity could potentially reverse balding.
research The Expression of Insulin-Like Growth Factor 1 in Follicular Dermal Papillae Correlates with Therapeutic Efficacy of Finasteride in Androgenetic Alopecia
Higher IGF-1 levels in hair follicles link to better finasteride results for hair loss.
research Transcriptional Activation of CCN1 and CCN2, Targets of Canonical Wnt Signal, by Ascorbic Acid 2-Phosphate in Human Dermal Papilla Cells
Vitamin C derivative may promote hair growth by activating specific genes.
research The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle
The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.
research Minoxidil Activates β-Catenin Pathway in Human Dermal Papilla Cells: A Possible Explanation for Its Anagen Prolongation Effect
Minoxidil helps hair growth by activating the β-catenin pathway.
research Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells
High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
research TGF-β2 Is Specifically Expressed in Human Dermal Papilla Cells and Modulates Hair Folliculogenesis
TGF-β2 plays a key role in human hair growth and development.
research Differences in Expression of Specific Biomarkers Distinguish Human Beard from Scalp Dermal Papilla Cells
Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.
research 5α-Reductase Activity in the Human Hair Follicle Concentrates in the Dermal Papilla
The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
research Androgen Receptor Accelerates Premature Senescence of Human Dermal Papilla Cells in Association with DNA Damage
Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.
research Biological Characterization of Cultured Dermal Papilla Cells and Hair Follicle Regeneration In Vitro and In Vivo
Cultured dermal papilla cells can regenerate hair follicles and sustain hair growth.
research Characterization of Human Dermal Papilla Cells in Alginate Spheres
Alginate spheres help maintain hair growth potential in human cells for hair loss treatment.
research Differential Molecular Signature of Dermal Papilla Cells from Balding and Non-Balding Scalp in 2D, 3D Culture and Co-Culture with Adipose-Derived Stem Cells
Dermal Papilla Cells grown in 3D and with stem cells better mimic natural hair growth conditions than cells grown in 2D.
research Balding Hair Follicle Dermal Papilla Cells Contain Higher Levels of Androgen Receptors Than Those From Non-Balding Scalp
Cells from balding scalps have more androgen receptors than cells from non-balding scalps.
research Androgen-Inducible TGF-β1 from Balding Dermal Papilla Cells Inhibits Epithelial Cell Growth: A Clue to Understanding Paradoxical Effects of Androgen on Human Hair Growth
Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.
research Sphere Formation Increases the Ability of Cultured Human Dermal Papilla Cells to Induce Hair Follicles from Mouse Epidermal Cells in a Reconstitution Assay
Forming spheres boosts the ability of certain human cells to create hair follicles when mixed with mouse skin cells.
research Induction of Versican by Ascorbic Acid 2-Phosphate in Dermal Papilla Cells
Vitamin C derivative increases versican in cells, potentially aiding hair growth.
research Restoration of Hair-Inductive Activity of Cultured Human Follicular Keratinocytes by Co-Culturing with Dermal Papilla Cells
Growing hair cells with dermal cells can potentially treat hair loss.
research Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes
A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.
research Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla
Male pattern baldness involves hormones and cell signals affecting hair growth.
research Hair Follicle Stem Cell Differentiation Is Inhibited Through Cross-Talk Between Wnt/β-Catenin and Androgen Signaling in Dermal Papilla Cells From Patients With Androgenetic Alopecia
Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.
research Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla
All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
research Identification of Androgen-Inducible TGF-β1 Derived from Dermal Papilla Cells as a Key Mediator in Androgenetic Alopecia
TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.
research Keratinocyte Growth Inhibition Through the Modification of Wnt Signaling by Androgen in Balding Dermal Papilla Cells
Androgens slow hair growth by altering Wnt signaling in balding cells.