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Leflunomide is effective for rheumatoid arthritis but has significant side effects.

Swedish men with the E213 A-allele of the androgen receptor have a lower risk of prostate cancer.

Certain gene variations in AKT2 are more common in women with PCOS and are linked to higher levels of specific hormones and symptoms.

Mice with a changed Hr gene lose and regrow hair due to changes in the gene's activity.

Creating a supportive environment is crucial for repairing heart tissue without using actual heart cells.

Cross-section trichometry is an accurate method to measure hair loss and growth.

Certain gene variations may increase the risk of alopecia, and platelet-rich plasma treatment can improve hair density in those with hair loss; a rare case of facial Becker's nevus was linked to uneven beard growth.

No effective treatment exists to stimulate hair growth in atrichia with papular lesions.

Some Greek melanoma patients have gene mutations linked to increased cancer risk, a new color feature helps diagnose melanoma, the incidence of a skin condition in the Netherlands is rare, and a gene possibly affects male-pattern baldness.

Lactic acid cream can help improve skin bumps known as eruptive vellus hair cysts.

Umbilical cord blood transplantation improved the boy's symptoms despite complications.

The document concludes that Borrelia afzelii causes a skin condition in France, a gene is linked to hair loss in Caucasian women, and various genetic mutations affect skin diseases.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.