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A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

DHT in the human prostate is produced through multiple pathways, not just from testosterone.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.