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Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Some medicinal plants can help heal wounds and may lead to new treatments.

Stem cell self-renewal is complex and needs more research for full understanding.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Turmeric may have benefits for skin health, but more research is needed to confirm its effectiveness.

Low fluence photoepilation temporarily removes hair by targeting the hair follicle's pigmented area without severe damage.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Skin-derived precursors in hair follicles come from different origins but function similarly.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.