14 citations
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January 2018 in “Endocrine” This report describes a three-generation family with Cantú syndrome linked to a novel ABCC9 gene variant, featuring acromegaloid appearance and hypertrichosis without growth hormone abnormalities, and suggests a potential association with pituitary adenomas.
April 2024 in “JCEM case reports” In this case study, a 44-year-old woman with an adrenal adenoma secreting both cortisol and androgens developed Cushing syndrome and significant virilization, but experienced major symptom improvement following surgical removal of the benign tumor.
5 citations
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December 2004 in “Dermatology” This review describes two cases of young women with primary amenorrhea and hyperandrogenemia, suggesting that adrenal tumors should be considered in patients with significantly elevated circulating testosterone levels.
10 citations
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December 2015 in “Clinics in Dermatology” This review highlights the eye and skin manifestations of endocrine-related metabolic diseases but provides no new clinical results.
78 citations
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November 2008 in “Fertility and Sterility” Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.
2 citations
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November 2011 in “InTech eBooks” This article reviews the types and characteristics of adrenal cortex tumors, including their hormone secretion and detection as incidental findings, but presents no new research results.
3 citations
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February 2018 in “Journal of evolution of medical and dental sciences” This study found that among patients with sex cord stromal ovarian tumors, 11% exhibited signs of virilization, requiring thorough clinical evaluation to rule out non-neoplastic causes.
247 citations
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August 2011 in “European Journal of Epidemiology” This article outlines the rationale, design, major findings, and updated objectives of the ongoing Rotterdam Study, without presenting new research data.
2 citations
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November 2012 in “InTech eBooks” The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
4 citations
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November 2013 in “Journal of IMAB - Annual Proceeding (Scientific Papers)” This report presents a case of functioning adrenocortical oncocytoma in a 9-year-old girl with virilization symptoms, successfully treated with laparoscopic surgery.
32 citations
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January 2010 in “Journal of Korean Medical Science” This case report describes a rare instance of functioning adrenocortical oncocytoma in a 14-year-old girl with virilization and reviews related literature.
September 2025 in “Current Oncology” This review highlights the potential roles of long non-coding RNAs (lncRNAs) in malignant brain tumors, reporting that further research into their involvement in therapy resistance and cancer pathways could improve diagnosis and treatment outcomes.
October 2022 in “Frontiers in Endocrinology” This review discusses recent advancements in omics and gene editing technologies for studying neuropeptides and receptors in fish, but reports no new experimental findings; the authors highlight the need for further research in this area.
August 2017 in “Journal of pediatric surgery case reports” This case report details a functioning adrenocortical oncocytoma in a 3-year-old girl with hirsutism and virilization, highlighting its rarity in childhood and including a literature review without new clinical data.
December 2023 in “Indian Journal of Endocrinology and Metabolism” In this case report from People's College of Medical Sciences, a 20-year-old man initially misdiagnosed with Addison's disease was ultimately found to have strongyloidiasis, with his symptoms and weight loss improving after antihelminthic treatment.
22 citations
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November 2017 in “Scientific Reports” This study found that, despite a major depletion of SOX2-expressing stem cells in the pituitary, there was no effect on endocrine cell homeostasis or response to certain stressors in adult mice.
September 2023 in “Fides et Ratio” This paper reviews the current lack of evidence on the safety and effectiveness of gender-affirming therapies in minors with gender dysphoria, highlighting ethical and legal concerns, including possible long-term consequences such as infertility.
17 citations
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May 2012 in “Clinical Endocrinology” This study found that surgical normalization of testosterone in hyperandrogenic women with ovarian androgen-secreting tumors did not significantly change body weight or insulin sensitivity after 12 months.
5 citations
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March 2001 in “Clinics in Dermatology” This article explores evidence for a rational strategy in the endocrine and metabolic management of patients with excess body hair or scalp loss and reports no new clinical results.
September 2024 in “Brazilian Journal of Case Reports” In this case study, a 62-year-old woman with severe hyperandrogenism underwent a clomiphene test, which suggested an ovarian origin for her condition, leading to the discovery of a Leydig cell tumor after a bilateral oophorectomy.
63 citations
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March 2011 in “Clinical Endocrinology” This review examines the evaluation and management of hirsutism and hyperandrogenism in postmenopausal women and reports no new clinical findings.
19 citations
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July 2013 in “The obstetrician & gynaecologist” This review discusses diagnostic criteria for polycystic ovary syndrome and highlights the challenges and risks of misdiagnosing women with other hyperandrogenism causes; it reports no clinical results.
2 citations
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September 2004 in “Fertility and sterility” This review discusses the cosmetic and health implications of hirsutism and highlights its potential link to serious underlying disorders, but it presents no new clinical findings.
1 citations
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November 2011 in “Open access journal of contraception” This article reviews the role of androgens and oral contraceptives in acne pathogenesis and management but presents no new clinical results.
August 2025 in “Fabad Journal of Pharmaceutical Sciences” This review highlights that bicalutamide, a non-steroidal antiandrogen used in prostate cancer treatment, is mainly effective through its (R)-enantiomer and emphasizes the need to monitor its adverse effects despite its targeted antiandrogenic action.
August 2019 in “Research Square (Research Square)” This study explored how long non-coding RNA mediates the effects of FGF5 on the hair follicle development and villus growth of Liaoning cashmere goats.
5 citations
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February 2023 in “European journal of endocrinology” This study found that older patients with Cushing's syndrome had fewer typical symptoms of hypercortisolism, more comorbidities, and were more often treated conservatively compared to younger patients.
October 2017 in “Springer eBooks” A thorough initial check-up is essential before sperm banking to ensure the best chance of preserving good quality sperm.
January 2016 in “Dermatology Review” This review details various skin manifestations linked to different endocrine disorders but does not report any new clinical results.
55 citations
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July 1999 in “Clinics in Sports Medicine” This review discusses recent data on the use of anabolic-androgenic steroids and other steroid compounds and reports no new clinical results.