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Low and ultralow doses of flutamide can cause liver damage in young women with high androgen levels, regardless of dose or birth control use, with higher risk for those with higher BMI and liver enzyme levels before treatment.

Green-synthesized nanoparticles can effectively target cancer cells, reducing side effects and improving treatment.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Poor maternal nutrition can lead to fewer wool follicles in Chinese Merino sheep.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

Blocking enzymes that help the virus enter cells could be a promising way to treat COVID-19.

Patients with Shwachman-Diamond syndrome often get misdiagnosed due to a wide range of symptoms, including immune system problems and bone abnormalities.

Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.

Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.

A specific microRNA, chi-miR-30b-5p, slows down the growth of hair-related cells by affecting the CaMKIIδ gene in cashmere goats.

Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.

Wound covers with α-13'-COOH from vitamin E can improve and speed up wound healing.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

The ketogenic diet can worsen biotin deficiency, suggesting a need for biotin supplements.

The document says PCOS is a common hormonal disorder in women, diagnosed by certain criteria, and managed with lifestyle changes and various medications.

Polycystic ovary syndrome (PCOS) is a major health issue for women in Egypt, affecting 14% of fertile women and 37.5% of infertile women.

A mix of Panax ginseng and bee-pollen may help prevent prostate enlargement in rats.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Key genes linked to hair growth and cancer were identified in hairless mice.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Darkened knuckles can be an early sign of insulin resistance.

Obesity is linked to skin conditions like acanthosis nigricans and skin tags, which may indicate high insulin levels.

Lower zinc levels may predict less effective hair loss treatment.

HIV-positive pregnant women are more likely to experience severe bleeding, and a pregnant woman with familial hypertriglyceridemia had a successful early delivery with special care.

The review concludes that more research is needed to better improve the health outcomes for people with Polycystic Ovarian Syndrome.

PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.

The study found a way to improve a skin-applied minoxidil formula using a specific design method.

Manage PCOS in primary care with weight loss, psychological support, medication, and monitoring for health risks.