Familial Hypertriglyceridemia in Pregnancy

    Alexandria J. Hill, Luis D. Pacheco, George R. Saade, Gary D.V. Hankins
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    TLDR HIV-positive pregnant women are more likely to experience severe bleeding, and a pregnant woman with familial hypertriglyceridemia had a successful early delivery with special care.
    The document reported on a study involving 321 pregnant women in Zambia, which found that HIV-positive women had nearly double the odds of experiencing severe hemorrhage compared to HIV-negative women, suggesting an increased risk of hemorrhage-related maternal mortality in HIV-positive patients. This association was observed even after adjusting for confounding factors such as age, parity, and study site, although the study was limited by missing HIV data and its design, which did not allow for an exploration of underlying mechanisms. Additionally, the document described the management of a 21-year-old pregnant woman with familial hypertriglyceridemia, a condition that can lead to complications like acute pancreatitis, who successfully delivered at 31 weeks following a regimen of a low-fat diet, omega-3 fatty acids, and medication. Furthermore, it briefly mentioned a cross-sectional observational study in Egypt that estimated the prevalence of polycystic ovary syndrome (PCOS) among fertile and infertile women using the Rotterdam diagnostic criteria.
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