Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study evaluated microneedling's effect on hair loss, finding a minor reduction in SALT scores for androgenetic alopecia patients, but no significant change for fibrosing or alopecia areata groups. Further skin biopsy analyses are pending to explore other changes beyond SALT scores.

In this study, researchers developed an optimized formulation of a traditional ethnomedicinal recipe from East Nusa Tenggara, which demonstrated strong antioxidant activity and significantly enhanced hair growth in a mouse alopecia model, compared to control groups.

This study investigated NNAT expression in embryonic and postnatal rat tissues, finding its localization in both undifferentiated and differentiated cells across tissues such as the pancreas, tongue, and testis.

This study found that melatonin enhanced whisker growth in vitro and identified MT1 receptor presence in the granular layer of mouse epidermis and the outer root sheath, suggesting potential for hair growth treatment.

This case study describes a 33-year-old woman with chronic myelogenous leukemia who developed nonscarring alopecia after starting nilotinib therapy, linked to perifollicular inflammation.

5% ET-02 is a more effective and safe treatment for hair loss than current options.

The researchers suggest that combining microneedle technology with nanocarriers could enhance drug delivery systems for treating central neurological diseases due to nanoparticles' ability to prolong blood circulation time and improve brain targeting.

This study found that combining 308-excimer phototherapy with intramuscular triamcinolone acetonide was effective and well tolerated for treating resistant alopecia totalis, showing a 90% overall response rate in the ten patients studied, with the best results observed in younger patients.

This study found that the proteins GDNF, NTN, GFRα-1, GFRα-2, and c-Ret are differentially expressed during various stages of the human hair follicle cycle, with potential implications for hair biology.

This study concluded that the combination 3 of the Nusa Tenggara Timur Ethnomedicinal Formula shows strong antioxidant activity and significantly increases hair follicle thickness in a chemotherapy-induced alopecia model in mice.

In this study, Natural Plant Extracts (NPE) promoted hair growth in mice by stimulating anagen growth and upregulating relevant gene expression, compared to controls with saline.

This study tested a hydrogel microneedle patch delivering T reg attractants in mice with alopecia, finding it boosted regulatory T cell numbers at the site, leading to hair regrowth without causing peripheral immunosuppression, suggesting a potential new approach for autoimmune skin disease treatment.

This review discusses androgen receptor targeting as a potential treatment strategy for triple-negative breast cancer and reports no new experimental outcomes.

This review discusses the role of mitochondria and evaluates methodologies for assessing mitochondrial function and toxicity, particularly in the context of HIV and antiretroviral treatments, but it reports no new empirical findings.

This review discusses various microneedle technologies for long-acting drug delivery, highlighting design considerations and challenges in bringing these minimally invasive devices to market, but it reports no new clinical results.

This case study reports generalized keratosis pilaris as a rare cutaneous side effect of nilotinib in a 40-year-old woman with chronic myeloid leukemia, highlighting the need for awareness among physicians.

This study found that nanobubble-encapsulated diclofenac with ultrasound-targeted microbubble destruction (DNBs-UTMD) can enhance the anti-tumor efficacy of Doxil® by regulating the tumor immune microenvironment, improving drug uptake, and increasing T cell responses while reducing immune-suppressive cells in the process.

This study found that HtrA2 inactivation in mnd2 mice is associated with delayed hair cycle phases and growth retardation of adipocytes, suggesting HtrA2's role in regulating adipogenesis-related hair growth.

In this study, combining L-cysteine and N-acetylcysteine with MET inhibition enhanced cytotoxicity in cancer cell lines by sensitizing them to MET inhibition through redox stabilization, suggesting a promising approach for improving MET-targeted cancer therapies without additional oxidative or chemotherapeutic stress.

This study found that NB-002 demonstrated clear antifungal activity and clinically significant nail clearing in subjects with distal subungual onychomycosis and ≤50% nail involvement, compared to a vehicle treatment.

This study found that using an electrical microneedling device enhanced the penetration of liposomal melanin-fluorescein into hair structures and widened the follicular infundibulum in ex vivo human skin models.

This study found that an aqueous extract of Bacopa procumbens improved motor function and preserved neuronal structure in a mouse model of Parkinson's disease, suggesting its neuroprotective potential.

This study found that melatonin implants in cashmere goats significantly altered the expression pattern and co-expression of miRNAs, suggesting a possible role in inducing a second growth of cashmere.

This study found that GTx-024 significantly increased total lean body mass and improved physical function in healthy elderly men and postmenopausal women, suggesting potential use for muscle wasting conditions.

This study found that multi-walled carbon nanotubes promoted root hair growth in certain plants, with results indicating they modulate nitric oxide and ethylene pathways crucial to this development.

In this case report, microneedling combined with PRP improved hair density and thickness in a 40-year-old man with androgenic alopecia, without side effects, suggesting it as a therapeutic option for those avoiding long-term pharmacotherapy.

This review summarizes the application of microneedles in treating various skin diseases and highlights challenges like low drug loading, noting no new clinical results are reported.

Low-dose oral naltrexone may help reduce inflammation in some scarring alopecia patients.