TLDR Neuronatin is found in various cells of rat tissues and has a unique location in sperm cells.
The study from October 19, 2018, investigated the expression and intracellular localization of Neuronatin (NNAT) in embryonic and postnatal rat tissues such as the pancreas, tongue, whisker hair follicle, and testis. The research found that NNAT was present in both undifferentiated and differentiated cells in these tissues. In the whisker hair follicles, NNAT was found in the inner root sheath. The study also discovered a new intracellular location for NNAT in the acrosomes in spermatozoa. The findings suggested that NNAT localization in the endoplasmic reticulum and its interaction with sarco/ER Ca2+-ATPase isoform 2 (SERCA2) were cell or tissue-specific properties.
7 citations,
December 2011 in “Annals of anatomy” Involucrin helps strengthen the inner parts of human hair.
87 citations,
July 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.
48 citations,
May 1991 in “The journal of investigative dermatology/Journal of investigative dermatology” Trichohyalin is also found in the outer layers of normal human skin.
2 citations,
March 2019 in “Journal of Histochemistry and Cytochemistry” Neuronatin is found in specific cells within rat testis, hair follicles, tongue, and pancreas, suggesting it has various roles in tissue development and function.
11 citations,
September 2016 in “Journal of virological methods” Rabies virus was found in specific skin cells of rabid dogs' muzzles, suggesting these cells could help diagnose rabies.
July 2022 in “Research Square (Research Square)” Certain miRNAs may play a role in sheep hair follicle development, which could help improve wool production.
5 citations,
October 2022 in “BMC genomics” Certain microRNAs are important for sheep hair follicle development and could help improve wool quality.
62 citations,
January 2000 in “Developmental dynamics” Notch-related genes play a key role in the development and cycling of hair follicles.
