Melatonin Receptor MT1 Is Expressed in Mouse Skin and In Vitro Melatonin Treatment Enhances Whisker Growth

January 2013 in “ Journal of clinical & experimental dermatology research ”

melatonin melatonin receptor MT1 epidermal keratinocytes outer root sheath keratinization hair growth

TLDR Melatonin may help whisker growth in mice.

The study aimed to identify the localization of the melatonin receptor MT1 in mouse skin and to assess the effects of melatonin on whisker growth in vitro. It was found that MT1 is expressed in the granular layer of mouse epidermal keratinocytes and in the outer root sheath. Additionally, when mouse whiskers were cultured in media with varying concentrations of melatonin, there was an enhancement in whisker growth. These findings suggest that melatonin may play a role in keratinization and could potentially be used as a treatment to promote hair growth.

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