How long have you tried topical melatonin?
    3/14/2024

    From the encyclopedia
    Melatonin →

    hormone commonly taken for sleep aid has some topical benefits for hair

    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    Dutasteride →

    Heavy duty finasteride that comes with higher risks

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💧 melatonin (topical) 1mg daily
    💧 minoxidil (topical) 8%
    💊 dutasteride (oral) 30mg
    💧 spearmint oil (topical) 20 drops
    💧 peppermint oil (topical) 20 drops
    💧 RU58841 (topical)
    💧 finasteride (topical) 0.1mg-0.25mg once a day
    💧 doxycycline (topical)
    💧 antihistamine (topical)
    the tone is 😐 neutral.

    Other terms

    The conversation is about the effectiveness of topical melatonin for hair loss, asking for details on dosage, frequency, duration of use, results, and brand information. An update includes a skeptical view on the studies regarding melatonin's effectiveness.
    View this post in the Community →

    Similar Community Posts Join

    5 / 5 results

      community Combining Ru58841 with my Topical Formula

       3 upvotes 1 year ago
      A user is combining RU58841 with a topical formula containing finasteride, dutasteride, minoxidil, triamcinolone, caffeine, and other ingredients. They have just started using it and report no side effects so far.

      community Topical Dutasteride 0.025% 2ml once a week

       10 upvotes 2 years ago
      A user discusses using topical dutasteride 0.025% once a week for hair maintenance, alongside fortified minoxidil, RU58841, and Reviv Hair Serum. They seek feedback on the effectiveness of this regimen.

      community Diffuse thinning is the worst. Nothing helps.

      in Update 10 months ago
      The user is experiencing diffuse thinning and has tried treatments like topical and oral finasteride, oral dutasteride, topical minoxidil, microneedling, melatonin, and caffeine without success. Despite using these treatments for over four years, the user reports continued hair thinning and is considering trying RU58841.

      community Doing nuclear stack. Is there anything else I could do?

      in Treatment  6 upvotes 1 year ago
      The conversation discusses a comprehensive hair regrowth regimen including Dutasteride, Finasteride, microneedling, RU58841, oral and topical Minoxidil, Tretinoin, and Vitamin D3. Suggestions include dropping Finasteride, increasing Dutasteride, and considering additional treatments like caffeine, melatonin, and laser therapy, while emphasizing the effectiveness of Dutasteride and Minoxidil.

      community biolabshop RU58841 source legit??

      in Product  1 upvotes 1 year ago
      The conversation is about using Biolabshop's RU58841 product, which includes GHK-Cu and melatonin, to improve hair quality and combat hair loss. The user has previously used finasteride, minoxidil, and Anageninc’s RU58841 with success and seeks feedback on the new product, especially from those on anabolic steroids or hormone treatments.

    Related Research

    6 / 6 results
      Therapeutic Strategies for Treating Hair Loss

      research Therapeutic strategies for treating hair loss

      42 citations , March 2006 in “Drug Discovery Today: Therapeutic Strategies”
      This article discusses the need for rational strategies in developing hair loss drugs targeting specific events in hair follicle cycling, reporting no clinical findings but emphasizing the importance of understanding molecular controls.
      Androgenetic Alopecia: An Update on Pathogenesis and Pharmacological Treatment

      research Androgenetic Alopecia: An Update on Pathogenesis and Pharmacological Treatment

      August 2025 in “Drug Design Development and Therapy”
      This review article examines current drugs for androgenetic alopecia, focusing on their mechanisms and clinical efficacy, noting that while finasteride and minoxidil are commonly approved treatments, new drugs targeting different pathogenic pathways have emerged, offering a broader understanding and reference for AGA treatment options.
      Drug Discovery for Alopecia: Gone Today, Hair Tomorrow

      research Drug discovery for alopecia: gone today, hair tomorrow

      70 citations , February 2015 in “Expert Opinion on Drug Discovery”
      This review discusses current knowledge on the biological mechanisms of different types of alopecia but reports no new clinical findings; the authors highlight future research directions, especially regarding epidermal stem cells and immune pathways.
      New Therapeutics in the Management of Androgenetic Alopecia

      research Nouvelles thérapeutiques dans la prise en charge de l’alopécie androgénétique

      March 2025 in “HAL (Le Centre pour la Communication Scientifique Directe)”
      This thesis investigates the underlying mechanisms and treatment options for androgenetic alopecia, highlighting the molecular roles of androgens and genetic predispositions, and evaluates current and emerging therapies, such as PROTACs and Janus Kinase inhibitors, to enhance patient management.