Diffuse thinning is the worst. Nothing helps. Update 11/5/2025
The user is experiencing diffuse thinning and has tried treatments like topical and oral finasteride, oral dutasteride, topical minoxidil, microneedling, melatonin, and caffeine without success. Despite using these treatments for over four years, the user reports continued hair thinning and is considering trying RU58841.
View this post in the Community →
Similar Community Posts Join
6 / 6 resultscommunity M26 Diffused Thinner - 6.5 months post-transplant, 2+ years on fin/min, now on oral dut and topicals
A 26-year-old male experienced hair thinning since age 18 and tried various treatments, including topical minoxidil, oral finasteride, and a hair transplant. He is currently using topical finasteride, minoxidil, tretinoin, hydrocortisone, and oral dutasteride, and is satisfied with the results 6.5 months post-transplant.
community I thought I’d be the perfect candidate for regrowth since I only had diffuse thinning on my crown. 9 months later of Oral Min and Fin and I’m worse off than when I started.
The user experienced worsening hair loss despite using oral minoxidil, finasteride, and topical minoxidil for nine months. They are considering switching to dutasteride and reducing ketoconazole shampoo due to its drying effects.
community No regrowth after oral min, topical fin, min, and tret: Aggressive diffuse/hairline recession in 2 years
A user experienced no hair regrowth after using oral minoxidil, topical finasteride, minoxidil, and tretinoin, and reported side effects from oral finasteride. They are considering switching to dutasteride or using hair fibers for better results.
community Aggressive diffuse thinning after 1 year of fin and min
The user is experiencing aggressive diffuse thinning despite using 1mg oral finasteride daily, topical minoxidil twice, microneedling, and Nizoral for seborrheic dermatitis. They are considering switching to dutasteride or RU58841 but are advised to seek a second opinion to determine the cause of hair loss.
community 18M Diffuse thinning with 7ng/mL Vit D. Is it just the deficiency or is 0.5mg Fin mandatory?
An 18-year-old with diffuse hair thinning is considering switching from a topical Minoxidil 10% + Finasteride 0.1% solution to Minoxidil 5% foam and oral Finasteride 0.5mg, while also addressing vitamin D deficiency and potential scalp inflammation. Users suggest using Nizoral shampoo for inflammation, considering dutasteride for better results, and maintaining vitamin D levels to protect hair follicles from DHT.
community 1 year of .5mg oral dut, .3% topical fin and 6% topical min everyday
A 25-year-old is experiencing hair thinning despite using 0.5mg oral dutasteride, 0.3% topical finasteride, and 6% topical minoxidil daily for a year. They are considering increasing dutasteride dosage and exploring other treatments like microneedling and KX 826, while seeking further medical opinions on their condition.
Related Research
6 / 6 results
research Investigating the Safety and Efficacy of Platelet-Rich Plasma (PRP) Treatment for Female Androgenetic Alopecia: Review of the Literature
This review discusses the use of platelet-rich plasma for treating female androgenetic alopecia, reporting that it shows high patient satisfaction and improved quality of life in affected women.
research Minoxidil: a comprehensive review
This study reported that while topical minoxidil exhibits hair regrowth in androgenetic alopecia, oral minoxidil 5 mg/day was more effective than topical forms after six months, with low doses also potentially effective for women and other hair loss types.
research Guava (Psidium guajava L.) Leaf Extract as Bioactive Substances for Anti-Androgen and Antioxidant Activities
This study suggests that guava leaf extract may inhibit hair loss by downregulating genes involved in androgen synthesis, potentially offering a natural alternative for treating androgenetic alopecia.
research A review of hormonal therapy for female pattern (androgenic) alopecia - eScholarship
This review explores potential treatments for female androgenetic alopecia, noting that anti-hormonal therapies may be beneficial for some women, but emphasizes the need for further research and effective solutions.
research Efficacy and Safety of Oral Minoxidil 5 mg Once Daily in the Treatment of Male Patients with Androgenetic Alopecia: An Open-Label and Global Photographic Assessment
This study found that low-dose oral minoxidil 5 mg daily significantly increased hair growth in men with androgenetic alopecia over 24 weeks, with increased hair count and vertex area improvement, though most experienced hypertrichosis and some had pedal edema.
research Hair growth-promotion effects at the cellular level and antioxidant activity of the plant-based extract Phyllotex™
This study suggests that the herbal formulation Phyllotex™ may promote hair growth in androgenetic alopecia by enhancing cell proliferation and reducing oxidative stress and TGF-β1 expression in vitro.