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270-300 / 1000+ resultsresearch Recyclable Polymerizable Deep Eutectic Solvent-Based Three-Dimensional-Printed Dissolving Microneedles with pH-Responsive Delivery of ZIF-8-Loaded Minoxidil for Hair Loss Therapy
This study described a novel three-dimensional-printed microneedle system designed for improved transdermal delivery of minoxidil to treat hair loss, demonstrating effective hair regrowth and safety in a mouse model while allowing sustainable needle base recovery.
research Efficacy and Cardiovascular Safety of Low-Dose Oral Minoxidil for Adult Androgenetic Alopecia and Female Pattern Hair Loss: A Structured Evidence Map and SWiM Narrative Synthesis
This review discusses low-dose oral minoxidil for adult androgenetic alopecia and female pattern hair loss and reports no clinical results; it provides a transparency archive with review materials.
research Nanocrystal Structure of Minoxidil: A Safe Stimulator for Hair Growth Factor for C57BL/6 Mice
In this study, minoxidil nanoparticles significantly increased hair growth rate in C57BL/6 mice compared to traditional minoxidil, suggesting enhanced effectiveness and potential as a new formulation.
research Metabolic syndrome
This discussion covers various nail disorders, including tumors and non-neoplastic issues, emphasizing that not all nail abnormalities are due to fungal infections, but it reports no new clinical findings.
research 72707 Effects of Oral Nicotinamide Mononucleotide (NMN) Supplementation on Hair: Influence of Fatigue on Treatment Outcomes
research Maternal androgen excess significantly impairs sexual behavior in male and female mouse offspring: Perspective for a biological origin of sexual dysfunction in PCOS
In this study, prenatal androgen exposure was linked to altered sexual behaviors in both male and female mice, with specific effects on mounting and lordosis behaviors.
research A novel pathogenic variant of NECTIN4 gene in a child with ectodermal dysplasia-syndactyly syndrome
This case report describes a novel NECTIN4 gene mutation linked to ED-syndactyly syndrome 1 in a young girl, contributing to the understanding of this rare ectodermal dysplasia.
research Diagnosis by Hair Sample:A Rare Case of Netherton Syndrome in a 2-Year-Old Girl
This case report describes a 15-month-old girl with a history of dermatitis, eosinophilic esophagitis, and failure to thrive, leading to a suspected diagnosis of Netherton syndrome.
research Desnutrición en Anorexia Nervosa: enfoque psicosomático y tratamiento multidisciplinar Malnutrition in anorexia nervosa: psychosomatic approach an multidisciplinary treatment
This preliminary study explores the role of melancholic mania in anorexia nervosa, noting it may reinforce the condition's difficult-to-reverse pathology and is often accompanied by poor self-esteem and maternal fixation.
research Congenital cataract and slowly progressing facial skin lesions in a 5‐year‐old boy
This case report describes a five-year-old boy diagnosed with nevus comedonicus syndrome, a rare skin condition, characterized by asymptomatic skin lesions and a congenital cataract of the right eye, without inflammation or typical signs of related conditions.
research Alterations in nasal mucociliary activity in polycystic ovary syndrome
This study found that women with PCOS had significantly prolonged nasal mucociliary clearance time, which may increase their susceptibility to respiratory tract and middle ear infections.
research Low-dose oral minoxidil for treatment of androgenetic alopecia and telogen effluvium in a pediatric population: A descriptive study
In this study, low-dose oral minoxidil was found to improve hair density in 80% of pediatric patients with androgenetic alopecia or telogen effluvium, with mild side effects primarily reported.
research Amperometric detection of minoxidil in hair lotion using a glassy carbon electrode modified with gold nanostructures
In this study, researchers developed an electrochemical method using gold nanostructures on a glassy carbon electrode to detect minoxidil levels in hair lotions, and found it effectively quantified minoxidil in commercial products, revealing discrepancies in their labeled versus actual concentrations.
research A rare LMNA missense mutation causing a severe phenotype of mandibuloacral dysplasia type A: a case report
In this case report, researchers described a 6-year-old girl with severe mandibuloacral dysplasia type A, noting unique physical deformities and a rare homozygous LMNA gene mutation not commonly associated with the condition.
research Use of low-dose oral minoxidil for hair growth in transgender and gender non-binary adult patients: a retrospective cohort study
research Cellular Senescence and Aging in Myotonic Dystrophy
This review discusses the similarities between myotonic dystrophy and aging, highlighting the role of cellular senescence in its pathophysiology, and reports no new clinical findings; the authors note potential anti-aging therapy applications.
research 52952 Oral Minoxidil New York Times Coverage: The Impact on Patient Perceptions and Dermatologists’ Approaches to Androgenetic Alopecia
This study assessed the impact of a New York Times article on consumer interest in androgenetic alopecia treatments by surveying dermatologists about practice trends and analyzing online search data related to low dose oral minoxidil and hair loss from February 2022 to February 2023.
research Chitosan nanoparticles for targeting and sustaining minoxidil sulphate delivery to hair follicles
This study developed minoxidil sulphate-loaded chitosan nanoparticles that doubled drug delivery to hair follicles in vitro compared to a control solution, suggesting potential for improved alopecia treatment.
research Successful use of topical minoxidil in the treatment of hypotrichosis associated with desmoplakin mutations
This study reports that topical minoxidil 5% foam may effectively promote hair growth in congenital alopecia and hypotrichosis linked to desmoplakin mutations, as demonstrated by significant hair growth in an 8-year-old boy.
research The Suppression Effects of Fat Mass and Obesity Associated Gene on the Hair Follicle-Derived Neural Crest Stem Cells Differentiating into Melanocyte by N6-Methyladenosine Modifying Microphthalmia-Associated Transcription Factor
The FTO gene hinders stem cells in hair follicles from becoming pigment cells.
research Role of the Differentiation of Root Epidermal Cells in Nod Factor (from Rhizobium meliloti)-Induced Root-Hair Depolarization of Medicago sativa
This study found that the Nod factor from Rhizobium meliloti, particularly at concentrations of 10-8 and 10-7 M, induced specific membrane depolarization and root-hair deformation in Medicago sativa, depending on the stage of cell differentiation.
research Association between nodular melanoma depth and area-based socioeconomic status, healthcare access, and preventive services use in the United States
Melanoma thickness at diagnosis is linked to access to dermatologists and preventive services, not to socioeconomic status.
research Low-dose oral minoxidil (LDOM) and topical minoxidil: consensus recommendations for managing male and female pattern Hair loss in Hair transplant patients using a modified delphi process
This study established consensus-based guidelines for using low-dose oral and topical minoxidil in managing pattern hair loss for patients undergoing hair transplant surgery, recommending specific dosages, monitoring procedures, and timing for initiation post-surgery.
research Mucinosis folicular. Reporte de un caso pediátrico
This case report highlights a rare instance of follicular mucinosis in a 15-year-old male, emphasizing its self-limiting, benign course but noting the need for long-term monitoring due to potential association with mycosis fungoides.
research Sulfation of minoxidil by human liver phenol sulfotransferase
This study found that minoxidil is bioactivated through sulfation by the phenol-sulfating form of phenol sulfotransferase in human liver.
research ANTI-MÜLLERIAN HORMONE LEVEL AS A PREDICTIVE FACTOR IN THE DIAGNOSIS OF POLYCYSTIC OVARIAN SYNDROME IN DUHOK PROVINCE – KURDISTAN REGION, IRAQ
This study found that serum anti-müllerian hormone levels above 3.2 ng/ml are both sensitive and specific for diagnosing polycystic ovary syndrome, linked with increased ovarian size and menstrual disturbances.
research The MHS Hair Restoration Protocol: A Systems-Biology Integration of Nutritional Support, Microbiome Modulation, and Targeted Topical ECS Therapeutics
This study introduces the MHS Hair Restoration Protocol, a systems-biology model targeting hair follicle health through the gut-microbiome-endocannabinoidome axis and innovative topical treatments, emphasizing a holistic approach to pattern hair loss.
research Discrimination of Dysplastic Nevi from Common Melanocytic Nevi by Cellular and Molecular Criteria
This study identified molecular differences between dysplastic nevi and common melanocytic nevi, including altered keratinocyte differentiation, increased hair follicle-related molecule expression, and distinct immune microenvironment characteristics in dysplastic nevi.
research Potentiometric determination of Minoxidil in topical use pharmaceutical samples
This study described a potentiometric titration method for determining minoxidil, which showed recoveries of 97.4 to 98.7% and agreed with chromatographic results within a 90% confidence level.