Amperometric Detection of Minoxidil in Hair Lotion Using a Glassy Carbon Electrode Modified with Gold Nanostructures

    January 2026 in “ Microchemical Journal
    Mayara O. Silva, Thawan Gomes de Oliveira, Eleilton da Silva, Irlan S. Lima, Enzo M. Otto, Lucio Angnes
    TLDR A new method accurately detects minoxidil in hair lotions, revealing discrepancies in labeled content.
    The study successfully developed a method for detecting minoxidil (MX) in hair lotions using glassy carbon electrodes modified with gold nanostructures (AuNStr). This approach addresses the issue of counterfeit MX products, which are prevalent in the market. The modified electrodes demonstrated a 50% increase in peak current for MX detection compared to unmodified electrodes, with a limit of detection of 20 μmol/L. The method was applied to three commercial formulations, revealing discrepancies in the actual MX content compared to the labeled amounts. The results were validated against high-performance liquid chromatography, confirming the method's effectiveness.
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