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This study found that minoxidil nanoliposomes led to faster hair growth and reduced scalp bacteria in mice compared to free minoxidil.

This study found that DNMT1 promotes adipogenesis in hair follicle stem cells by regulating the miR-214-3p/MAPK1/p-ERK1/2 pathway, suggesting potential applications in stem cell therapy.

This study found that ALRN-6924, a clinical-stage dual inhibitor, can selectively protect human scalp hair follicles from paclitaxel-induced toxicity and damage by inducing transient cell cycle arrest in healthy cells without affecting cancer cells, potentially reducing chemotherapy-induced alopecia.

This article highlights the importance of recognizing, preventing, and reporting adverse drug reactions to the FDA's MedWatch program, but it presents no new research findings.

This study identified two novel mutations in the CDH3 gene causing HJMD in a Chinese patient, expanding the genetic and phenotypic understanding of the disorder.

In animal studies, this research found that minoxidil-loaded air-pocket microneedles improved hair loss treatment efficiency compared to topical application, while effectively sealing punctured skin openings.

This study highlights the clinical potential of microneedles as an innovative transdermal drug delivery system for treating various skin diseases with minimal pain and high patient compliance.

This study reports on a new semantic annotation approach used to identify substances in MEDLINE abstracts responsible for adverse drug reactions, with promising performance shown by a prototype system.

This review summarizes a 15-year collaboration on the role of synaptic-like vesicles in mechanosensory nerve terminals and suggests potential therapeutic implications for conditions like hypertension and muscle spasticity.

This review highlights the inadequacy of the "specificity paradigm" in drug design for complex diseases like Alzheimer's and cancer, suggesting a shift toward developing multitarget drugs to improve treatment efficacy by interacting with multiple targets through various mechanisms.

This study suggests a connection between the unfolded protein response and upregulation of NKG2D ligands in stressed hair follicles, highlighting a potential role of PRDX5 in alopecia areata pathogenesis.

This study describes the development of nanostructured lipid carriers for minoxidil as a potential alternative to conventional topical solutions, showing promise for use in topical formulations.

This study found that DrugNet, a network-based prioritization method, effectively improves drug repositioning tasks, achieving high performance in validation tests and clinical trial comparisons.

In this study, oral supplementation with NMN for 12 weeks in middle-aged Japanese women significantly increased hair growth density and diameter and improved subjective assessments of hair texture and quality of life, with no significant changes in hair hormone concentrations observed.

Progesterone increases alcohol tolerance and withdrawal anxiety, while DHEAS prevents them.

In this study, Gsdma1/2/3 knockout mice showed reduced epidermal hyperplasia and inflammation when induced by PMA, which was attributed to decreased EGFR-Stat3/Akt signaling due to a decrease in related ligands.

Neurosteroids may help metyrapone reduce cocaine addiction.

This review discusses the similarities between myotonic dystrophy and aging, highlighting the role of cellular senescence in its pathophysiology, and reports no new clinical findings; the authors note potential anti-aging therapy applications.

This study suggests that the regulation of GABA‐A δ subunit expression by ovarian progesterone-derived neurosteroids may influence seizure susceptibility in catamenial epilepsy.

Carbamazepine may cause reversible nail detachment.

This case report illustrates that pellagra can develop in patients with anorexia nervosa without typical signs of severe malnutrition, responding rapidly to nicotinamide and tryptophan therapy.

This study found that their newly developed ADRL framework significantly improved the accuracy of scalp tissue layer segmentation in HR-MR images compared to existing methods.

This study found that a patient with giant axonal degeneration had unique hair abnormalities such as trichorrhexis nodosa and altered S:N ratios, unlike her relatives but comparable to unrelated controls.

This study found that chronic ethanol exposure and withdrawal alter the expression and function of GABA-A receptors in rat hippocampal and cerebellar neurons, suggesting different roles for these receptors in controlling tonic inhibition.

This publication presents a library of geometric medicines designed to selectively target pathogenic bacteria and fungi with high precision while minimizing ecological harm, available for free on a non-commercial basis.

Scale created to measure hair loss in men and women; MK-386 reduces acne; Niaspan treats dyslipidemia; minoxidil increases heart rate.

This study found that conditional deletion of CD271 in mouse epidermis led to significant disorganization and increased thickness, suggesting CD271's crucial role in regulating skin differentiation and structure.

In this study, researchers found that dissolving microneedles made with hyaluronic acid enhanced the effectiveness of minoxidil in reducing hair loss and promoting hair growth in alopecia-affected mice more effectively than topical minoxidil alone, while using only 10% of the drug amount.