January 2009 in “Chinese Journal of Evidence-Based Pediatrics” This study reports that neonatal lupus erythematosus can involve various clinical manifestations, such as heart and liver impairments, with a long-term prognosis that may include progression to other autoimmune diseases in childhood.
January 2021 in “Figshare” This study developed a nanostructured lipid carrier for 17-α-estradiol that showed stable physicochemical properties and improved targeting to hair follicles in alopecia treatment.
January 2026 in “Pharmaceutical Development and Technology” This study found that nanostructured lipid carriers containing tea seed or lavender oil improved hair regrowth in female Wistar rats over 30 days, showing greater effectiveness compared to a commercial product and placebo, attributed to enhanced follicular penetration and stability.
28 citations
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March 2014 in “International Journal of Nanomedicine” This study developed lipid nanoparticles for delivering minoxidil and finasteride to the dermis and hair follicles, showing stability and a desired prolonged release, though with low skin penetration levels.
In this open uncontrolled study on microneedling as an adjuvant therapy for frontal fibrosing alopecia, researchers observed stable frontotemporal recession measurements while patients reported improvements in quality of life and a reduction in inflammatory activity parameters.
April 2023 in “Journal of Investigative Dermatology” This study suggests that linalool, a common allergen in personal care products, may contribute to frontal fibrosing alopecia pathogenesis by triggering immune responses and depleting hair follicle stem cells, especially in sensitized individuals.
July 2025 in “Journal of Investigative Dermatology” Discoid lupus erythematosus involves immune activation and fibrosis around hair follicles, with shared pathways across humans, dogs, and mice, suggesting potential treatments for both humans and animals.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that allergens like linalool found in personal care products may contribute to the pathobiology of frontal fibrosing alopecia by affecting immune responses and stem cell function in hair follicles.
4 citations
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February 2014 in “Proceedings of SPIE” This review discusses the diverse applications of low-level laser therapy in aesthetic dermatology, especially for managing alopecia, but notes that comprehensive literature on its effectiveness is lacking.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that in a mouse model of Focal Dermal Hypoplasia, treatment with lithium carbonate improved skin disease symptoms compared to controls, though disease severity varied and posed interpretation challenges.
1 citations
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July 2021 in “Current nanomedicine” This study found that nanostructured lipid carriers could serve as a promising vehicle for topical Acitretin delivery in psoriasis treatment, potentially reducing oral side effects and enhancing patient compliance.
February 2010 in “Journal of The American Academy of Dermatology” NB-002 is a promising new topical treatment for fungal nail infections, showing better results than a non-medicated option.
October 2023 in “Facial Plastic Surgery” This review discusses combining follicular unit excision (FUE) and linear strip excision (LSE) donor harvesting methods to optimize graft yield while minimizing donor depletion, but provides no new clinical results.
July 2026 in “Drug Delivery Letters” This review discusses the potential of nanostructured lipid carriers to improve herbal treatments for alopecia and reports no new clinical results, highlighting the need for further clinical trials and safety data.
19 citations
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April 2013 in “Drug Development and Industrial Pharmacy” This study highlights the significance of the hf pathway for the skin permeation of ionized and hydrophilic high molecular compounds, and the usefulness of hf-plugging in evaluating their skin permeability.
This study demonstrated that the IVL-DrugFluidic® platform is effective for mass-producing finasteride-loaded polymeric microspheres for long-acting injectables, maintaining stable drug release without an initial burst for a month.
17 citations
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October 2016 in “Artificial Cells Nanomedicine and Biotechnology” This study found that arginine-loaded lipidic nanoparticles improved hair follicle growth in male hamsters more effectively than an aqueous arginine solution.
6 citations
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February 2020 in “Journal of Cutaneous Pathology” This case report describes the histopathological features of nevus psiloliparus in an 11-year-old girl, noting "shadow" follicular units with loosely arranged collagen and reduced elastic fibers.
November 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study suggests that nanostructured lipid carriers loaded with spironolactone might improve localized delivery to hair follicles for treating androgenic alopecia, potentially minimizing systemic side effects.
63 citations
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October 2011 in “Archives of Dermatology” Isolated long hairs at the original hairline can help diagnose Frontal Fibrosing Alopecia.
July 2022 in “International Journal of Applied Pharmaceutics” This study concluded that the optimized caffeine-loaded nanostructured lipid carriers improved hair growth by enhancing permeation through skin layers more effectively than an existing market formula.
37 citations
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June 2000 in “Experimental dermatology” This study investigated a spontaneous mutation in mice resulting in hair abnormalities and elevated IgE levels, which resembles human Netherton's syndrome and monilethrix.
July 2022 in “Journal of Investigative Dermatology” This study found that the transcription factor Lef1 is crucial for normal skin and hair development and wound healing, highlighting its role in regulating essential genes and pathways in papillary fibroblasts.
January 2025 in “Medical Research Archives” This review discusses various applications of low level laser therapy and argues for a holistic evaluation of patients but reports no new clinical findings.
10 citations
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June 2019 in “Case reports in dermatology” This paper presents a case of a young male with linear and annular lupus panniculitis of the scalp, detailing trichoscopic findings and their correlation with histopathological features, but reports no new generalizable results.
1 citations
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March 2010 in “International Journal of Cosmetic Science” This study introduces a new device for measuring changes in hair stiffness and lubricity, which can help predict the effects of various hair treatments.
1057 citations
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November 2011 in “Annals of Biomedical Engineering” This review discusses the applications of low level laser therapy (LLLT) in wound healing, pain reduction, and treating various conditions, but reports no new clinical results; the authors highlight the need for randomized controlled trials for serious diseases.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study generated a transcriptomic map of human hair follicles, identifying compartment-specific gene expression profiles that can aid in developing targeted therapies for hair follicle disorders.
22 citations
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September 2011 in “Journal of Investigative Dermatology” This study found that impaired TCF/Lef1 signaling in mice leads to significant skin barrier defects due to altered lipid metabolism and epidermal differentiation.
2 citations
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November 2020 in “International Journal of Otorhinolaryngology and Head and Neck Surgery” The researchers reported that nasolabial flaps were effective for reconstructing small to intermediate oral cavity defects in early oral cancer patients, with overall good cosmetic and functional outcomes despite some complications.