TLDR Nevus psiloliparus lacks mature hair follicles but keeps other skin structures intact.
The document reported on the histopathological features of nevus psiloliparus, a rare fatty tissue nevus associated with encephalocraniocutaneous lipomatosis, in an 11-year-old girl. This condition was characterized by congenital alopecia, presenting as an irregularly shaped area of hair loss on the scalp. Histopathological examination revealed a near-complete absence of mature hair follicles, with preserved arrector pili muscles and mature adipocytes in the dermis. The study suggested that the pathogenesis might be linked to mosaic mutations in the fibroblast growth factor receptor 1. The transverse sections showed "shadow" follicular units with loosely arranged collagen and a scarcity of elastic fibers.
11 citations
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August 2017 in “American Journal of Dermatopathology” EVG staining helps tell apart follicular scars from follicular streamers, aiding in diagnosing different types of hair loss.
4 citations
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September 2013 in “Journal of Plastic Surgery and Hand Surgery” A girl with a rare syndrome had successful hair loss treatment with no relapse after 4 years.
38 citations
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December 2012 in “Journal of Cutaneous Pathology” EVG staining is a valuable, simple, and cost-effective method for diagnosing various skin conditions in dermatopathology.
80 citations
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March 2000 in “Journal of cutaneous pathology” The VVG stain effectively differentiates scar tissue from normal skin and helps classify types of permanent alopecia.
4 citations
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September 2013 in “Journal of Plastic Surgery and Hand Surgery” A girl with a rare syndrome had successful hair loss treatment with no relapse after 4 years.
1 citations
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January 2014 in “Indian journal of dermatology, venereology, and leprology” The symptoms described align more with Haberland syndrome, not Delleman-Oorthuys syndrome.
44 citations
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January 1999 in “Dermatology” Nevus comedonicus is a rare skin condition with grouped open pores, sometimes linked to other body issues.
38 citations
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June 2005 in “International Journal of Dermatology” A man with nevus comedonicus syndrome had multiple skin issues, including basal cell carcinomas, which improved with treatment.
31 citations
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January 2007 in “Journal of the American Academy of Dermatology”
