26 citations
,
September 2018 in “Journal of Molecular Cell Biology” This study observed that Endoglin is crucial for maintaining correct hair follicle cycling and stimulating hair follicle stem cell niches through feedback interactions involving Wnt/β-catenin and Bmp/Smad signaling pathways in a mouse model.
26 citations
,
July 2011 in “PubMed” The authors report a case where alopecia areata went into remission after H. pylori eradication, suggesting a potential link that could expand treatment options if further studies confirm it.
23 citations
,
August 2019 in “Proceedings of the National Academy of Sciences of the United States of America” Pollution exposure speeds up hair damage.
23 citations
,
April 1996 in “PubMed” This article reviews the role and clinical applications of 1,25-dihydroxyvitamin D3 and parathyroid hormone-related peptide in dermatology, with a focus on psoriasis treatment, and reports no new experimental findings.
23 citations
,
June 1993 in “PubMed” This study found that a vitamin B-group and L-cystine combination therapy improved hair quality and growth in women with diffuse effluvia, with one formulation showing greater efficacy than another and both performing better than placebo.
21 citations
,
October 2013 in “Molecular Biology of the Cell” This study found that the protein CCN2 in dermal papilla cells is a physiologically relevant suppressor of hair follicle formation by destabilizing β-catenin, which may help maintain stem cell quiescence.
20 citations
,
July 2000 in “PubMed” This article describes an organized diagnostic approach for identifying nonscarring and scarring alopecias to aid family physicians in making accurate in-office diagnoses, but it reports no new clinical findings.
19 citations
,
January 2012 in “International Journal of Trichology” This case series suggests that Propionibacterium acnes colonization may contribute to the development of hair casts and diffuse non-scarring alopecia, as patients' symptoms improved with antibiotics targeting the bacteria.
19 citations
,
October 1989 in “PubMed” This study found that sulfation of minoxidil occurs in hair follicles and proliferative keratinocytes, which may be linked to its hair growth stimulation effects.
18 citations
,
May 2017 in “Fertility Research and Practice” This study found that increased ovarian volume is associated with markers of insulin resistance in women with polycystic ovary syndrome, while follicle number was not linked to metabolic risk.
18 citations
,
January 2016 in “Skin appendage disorders” The paper suggests improving diagnosis and treatment of telogen effluvium but does not recommend a new classification system.
18 citations
,
November 2013 in “Molecules and Cells” This study found that a novel 3D in vitro culture condition improved stemness markers and proliferation potential in human dermal stem/progenitor cells compared to traditional 2D methods.
17 citations
,
September 2019 in “Journal of Cell Biology” This study found that despite carrying an activating Hras mutation, hair follicle stem cells integrate into normal skin without causing tumors, unlike similar mutations in the epidermis, suggesting unique tumor-suppressing mechanisms in hair follicles.
17 citations
,
October 1980 in “PubMed” In this study, sodium valproate achieved complete seizure control in 82% of children as monotherapy, with higher plasma levels potentially linked to resistant cases.
16 citations
,
November 2018 in “Singapore Medical Journal” This article reviews the clinical presentation, contributing factors, and prevalence of polycystic ovary syndrome but provides no original research findings.
16 citations
,
September 2016 in “Experimental Dermatology” This review provides guidance on using two-photon microscopy for real-time and long-term visualization of stem cell activity in live mice skin, focusing on its application in researching skin and stem cell biology.
14 citations
,
January 1977 in “PubMed” This study found that a specific variant in hair keratin was present mainly in Caucasian samples, with few exceptions showing likely Caucasian admixture.
13 citations
,
May 1987 in “PubMed” This review explores the mechanisms and clinical trials of topical minoxidil for hair loss but presents no new clinical findings, emphasizing the need for better understanding of hair loss etiology for effective treatments.
13 citations
,
November 2018 in “Annals of Plastic Surgery” This article presents a surgical approach for nonshaven follicular unit extraction in hair transplantation, describing its application across various conditions with an average graft transection rate of 8.2%.
11 citations
,
January 2017 in “Journal of Endocrinology/Journal of endocrinology” This study observed that female mice with disrupted 5α-reductase 1 showed increased insulin resistance and hepatic steatosis, suggesting altered glucocorticoid metabolism contributes to metabolic disorders.
11 citations
,
April 2013 in “SpringerPlus” This study reports that melanocytes form a defined photoresponsive network in the skin that reads environmental light cycles and may influence the sleep-waking cycle similar to the pineal gland.
11 citations
,
March 1991 in “PubMed” This study found that in female patients with androgenic hair loss and hirsutism, complex hormonal disturbances include elevated cortisol and thyroid hormone imbalances, rather than elevated androgen levels alone.
11 citations
,
January 2011 in “Indian Dermatology Online Journal” This article discusses a proposed molecular mechanism linking dietary factors to acne but reports no new clinical findings.
10 citations
,
December 1992 in “PubMed” This report of three cases found that diagnosing hypercortisolism during pregnancy can be challenging, but early detection using unbound steroid levels and MRI could prevent severe complications.
10 citations
,
March 2015 in “PubMed” This paper demonstrates that scalp micropigmentation can effectively conceal scalp and hair deformities with high patient satisfaction, offering a non-surgical alternative cosmetic solution.
9 citations
,
September 1989 in “PubMed” This study observed that selenium levels were lower in Sudanese children with malnutrition compared to healthy German children, with a good correlation between selenium and glutathione peroxidase activity.
9 citations
,
January 1975 in “PubMed” In this study, researchers using a mouse model found that the hairlessness in nude mice is likely due to a shared defect in the thymus and skin, not thymic dysgenesis alone.
8 citations
,
January 1989 in “PubMed” This study found that applying minoxidil topically had no recognizable effect on hair follicle growth in newborn mice, though it highlighted apoptosis as a potential marker for hair regression research.
7 citations
,
January 2016 in “Methods in molecular biology” This study describes the process of isolating and analyzing multipotent stem cells from mouse hair follicles for potential use in tissue engineering and regenerative medicine.
7 citations
,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that thymus transplantation in athymic mice resulted in T-cell-driven hair follicle depigmentation and loss, without multiorgan autoimmune disease, highlighting mechanisms of tissue-specific tolerance.