Hyperprolactinemia and Hypophyseal Hypothyroidism as Cofactors in Hirsutism and Androgen-Induced Alopecia in Women

    March 1991 in “ PubMed ”
    J.B. Schmidt, A. Lindmaier, Spona J
    TLDR Hormonal imbalances, including high prolactin and thyroid issues, contribute to hair growth problems in women.
    The study conducted by J B Schmidt et al. in 1991 investigated the hormonal disturbances associated with androgen-dependent hair growth disorders in women, specifically focusing on hyperprolactinemia and hypophyseal hypothyroidism as cofactors. The research involved 46 women with androgenic hair loss and 27 with hirsutism, comparing their hormone levels to 27 women without endocrine disorders. The findings indicated that androstenedione was slightly elevated in hirsutism, while cortisol was significantly elevated in androgenic hair loss. The study also revealed that hypothyroidism was a significant finding in both conditions, with elevated TSH levels, and hyperprolactinemia was notably present in hirsutism. The research highlighted the complex hormonal interactions contributing to these conditions.
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