Hyperprolactinemia and Hypophyseal Hypothyroidism as Cofactors in Hirsutism and Androgen-Induced Alopecia in Women

    March 1991 in “ PubMed ”
    J.B. Schmidt, A. Lindmaier, Spona J
    TLDR Hormonal imbalances, including high prolactin and thyroid issues, contribute to hair growth problems in women.
    The study conducted by J B Schmidt et al. in 1991 investigated the hormonal disturbances associated with androgen-dependent hair growth disorders in women, specifically focusing on hyperprolactinemia and hypophyseal hypothyroidism as cofactors. The research involved 46 women with androgenic hair loss and 27 with hirsutism, comparing their hormone levels to 27 women without endocrine disorders. The findings indicated that androstenedione was slightly elevated in hirsutism, while cortisol was significantly elevated in androgenic hair loss. The study also revealed that hypothyroidism was a significant finding in both conditions, with elevated TSH levels, and hyperprolactinemia was notably present in hirsutism. The research highlighted the complex hormonal interactions contributing to these conditions.
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      community does lowering your prolactin levels regrow hair?

      in Research/Science  9 upvotes 2 years ago
      The potential of lowering prolactin levels to regrow hair, with a reference to Bayer's drug HMI 115 which has been indicated as having this effect. Treatments mentioned include Minoxidil and Finasteride, as well as RU58841.

      community how about progesterone cream?

      in Research/Science  22 upvotes 1 year ago
      Progesterone cream might help with hair loss by inhibiting DHT production and suppressing prolactin, which can increase DHT. Some dermatologists have used progesterone for hair loss treatment, and it has been effective, sometimes combined with minoxidil, finasteride, and hydrocortisone.

      community hmi115 is coming. Prepare yourselves for what's coming

      in Technology  108 upvotes 2 years ago
      The conversation discusses HMI-115, a potential cure for hair loss. Users share mixed opinions, with some expressing skepticism and others sharing anecdotal evidence of its effectiveness, including photos of significant hair regrowth from a trial participant.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 2 years ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

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