44 citations,
April 2017 in “Genes & development” Scientists found cells in hair that are key for growth and color.
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
August 2015 in “MOJ proteomics & bioinformatics” ePUKs could be valuable for regenerative medicine due to their wound healing abilities.
February 2022 in “Research Square (Research Square)” LGR5 is a marker found in hair follicle stem cells in various species and is important for hair growth and skin repair.
30 citations,
June 2017 in “Current stem cell research & therapy” Adipose-derived stem cells (fat cells) show promise in treating hair loss in both men and women.
2 citations,
April 2019 in “Journal of Investigative Dermatology” Gasdermin A3 causes hair follicle stem cells to activate too early, leading to hair loss.
September 2016 in “Journal of dermatological science” Epidermal stem cells use integrin β1 and α6 as markers and CD271+ cells help maintain skin health and heal wounds.
January 2019 in “Elsevier eBooks” Understanding stem cell environments is key to developing treatments for various diseases and injuries.
April 2023 in “Journal of Investigative Dermatology” The study found that aging hair follicle stem cells change behavior, leading to hair loss, but drugs targeting these cells may help restore hair growth.
April 2023 in “Advanced functional materials” The study created a tool that mimics natural cell signals, which increased cell growth and could help with hair regeneration research.
58 citations,
August 2015 in “The Indonesian Biomedical Journal” Different types of stem cells help maintain and heal skin.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Neoplasms hide in hair follicles to avoid the immune system.
December 2012 in “Journal of Dermatological Science” Wnt/beta-catenin signaling in the skin helps fat cell development during hair growth and repair.
550 citations,
December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.
August 2009 in “Mechanisms of Development” Adult hair follicle cells can create new hair follicles from corneal cells with the right support.
June 2007 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Hair can regrow in adult mice's skin after injury, and this regrowth doesn't come from existing hair cells but from skin cells in the wound, with Wnt7a protein helping this process. This could help treat baldness and scarring.
5 citations,
May 2020 in “Life science alliance” Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.
92 citations,
December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.
42 citations,
January 2017 in “Stem cells international” Adding hyaluronic acid helps create larger artificial hair follicles in the lab.
74 citations,
January 2013 in “Expert Opinion on Biological Therapy” The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.
May 2007 in “Science's STKE” Healing skin wounds in mice can create new hair follicles, and adjusting Wnt signaling could potentially reduce scarring and treat hair loss.
April 2023 in “Journal of Investigative Dermatology” Proper cell death regulation is crucial for normal hair follicle regeneration and skin remodeling.
January 2022 in “Stem cell biology and regenerative medicine” Improving dermal papilla cells can help regenerate hair follicles.
7 citations,
February 2023 in “Inflammation and Regeneration” The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.
May 2007 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Hair can regrow in adult mice's skin after injury, and this regrowth doesn't come from existing hair cells but from skin cells in the wound, with Wnt7a protein helping this process. This could help treat baldness and scarring.
May 2007 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Hair can regrow in adult mice's skin after injury, and this process can be boosted by increasing Wnt7a, a protein. This could potentially help treat baldness and change our understanding of hair growth.
Low-level laser therapy may help stem cells grow and function better, aiding in healing and tissue repair.
12 citations,
May 2019 in “Stem cell reviews” Fetal-maternal stem cells in a mother's hair can help with tissue repair and regeneration long after childbirth.
43 citations,
December 2008 in “Molecular biology of the cell” Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
October 2012 in “Medical Hypotheses” Artemis dysfunction might cause hair loss through telomere shortening.