12 citations
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September 2021 in “Stem Cell Reviews and Reports” This study suggests that StemMACS MSC Expansion Media is more suitable than PowerStem MSC1 media for expanding therapeutic adipose-derived mesenchymal stem cells, with less expression of negative markers and better chromosomal stability.
10 citations
,
April 2016 in “Research and reports in transdermal drug delivery” This review discusses the potential of follicular drug delivery systems to target the pilosebaceous unit and reports no new research findings.
9 citations
,
November 2017 in “International Journal of Nanomedicine” This animal study found that intravenous administration of anionic squarticles, a lipid nanoemulsion, increased survival rates in rats with amitriptyline overdose by mitigating adverse effects and restoring normal blood pressure, highlighting its potential as a detoxifying antidote.
7 citations
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February 2025 in “Stem Cell Research & Therapy” In a study using a mouse model, HF-MSCs were reported to enhance ovarian function in cyclophosphamide-induced premature ovarian failure more effectively than HU-MSCs, potentially by preventing ferroptosis in granulosa cells via the KEAP1/NRF2/HO-1 pathway.
6 citations
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March 2021 in “Cytotechnology” This review examines recent findings on COVID-19 pneumonia treatment using mesenchymal stem cells and reports no new clinical results; the authors highlight MSCs' potential due to their immunomodulatory and tissue-regenerative properties.
4 citations
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April 2021 in “Experimental and Molecular Medicine” This review examines host factors like ACE2 and TMPRSS2 in SARS-CoV-2 infection, exploring how genetic variants and advanced cellular analyses might clarify COVID-19's severity and heterogeneity; it reports no new results.
3 citations
,
July 2024 in “Frontiers in Pharmacology” This study demonstrates that Puerariae Lobatae Radix may regulate skin lipid metabolism by inhibiting sebaceous gland growth and reducing triglyceride secretion, highlighting its therapeutic potential for sebaceous gland-related conditions.
1 citations
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September 2025 in “Scientific Reports” This study reported that a colistin sulfate-loaded nanoemulgel showed improved antimicrobial activity and skin permeability compared to a CS solution, suggesting a potential new approach for treating severe infections caused by multidrug-resistant bacteria.
1 citations
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March 2025 in “Medical Molecular Morphology” This review discusses how androgens, commonly known for male reproductive roles, also influence the physiology and pathology of the human endometrium, though their exact roles in this tissue remain controversial and not fully understood.
1 citations
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November 2022 in “World Family Medicine Journal /Middle East Journal of Family Medicine” This study found that while participants in Jeddah, Saudi Arabia, had good knowledge about Vitamin D and recognized sunlight as a key source, there was inconsistency in their attitudes towards maintaining adequate Vitamin D levels.
February 2026 in “Human Cell” This study found that factors released by mesenchymal stromal cells can enhance the proliferation and migration of keratinocytes in vitro, which may contribute to improved understanding of their role in wound healing and potential applications in dermal regeneration therapies.
This study used a mouse model to reveal that S100A4-positive cells, specifically fibroblasts and immune cells, play a crucial role in nipple development, essential for successful lactation, despite no issues with mammary morphology or milk production.
In this study, researchers used a mouse model to identify an adipocyte-to-fibroblast conversion pathway that promotes mast-cell recruitment and dermal fibrosis in atopic dermatitis, suggesting a potential therapeutic approach to block this process and reduce inflammation and fibrosis.
February 2025 in “Scientific Reports” In this study, lipid metabolism was found to be reduced in scalp tissues of patients with androgenetic alopecia, and lipid supplementation enhanced hair growth-related gene expression in human dermal papilla cells, suggesting a potential role for lipids in promoting hair growth through HIF-1 signaling.
This study suggests that targeting the increased expression of SIX1 in systemic sclerosis may be a viable strategy for addressing dermal fibrosis.
April 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identifies key transcriptomic features and a necessary dermal niche for eccrine gland development, advancing potential regenerative approaches for these vital skin appendages.
September 2022 in “Institutional Repositories DataBase (IRDB)” Adipose-derived stem cells can be transformed into hair-forming cells using specific extracellular vesicles, offering potential for hair regeneration therapies.
March 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that the expression of VLCFA biosynthesis genes is suppressed in skin hyperplasia and cancer, which could influence keratinocyte function.
September 2019 in “University of Huddersfield Repository (University of Huddersfield)” In this study, nanoemulsion formulations were found to significantly enhance the skin retention of the antiseptic agent triclosan, with the optimal mixture being a low surfactant concentration, as demonstrated through quantitative and qualitative analysis using tape-stripping and micro CT scans.
This paper discusses advancements in forensic hair analysis, emphasizing a novel DART–HRMS method that improves the accuracy and efficiency of detecting drug use timelines.
January 2015 in “Durham e-Theses (Durham University)” This study found that glucose starvation and hypoxia are physiological triggers of ER stress in in vitro differentiated adipocytes, rather than high concentrations of saturated fatty acids, cholesterol, or proinflammatory cytokines.
233 citations
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February 2018 in “Polymers” This review examines the roles and benefits of chitosan in cosmetics and oral hygiene, highlighting its potential in the cosmeceutical market, but it reports no new results.
13 citations
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September 2024 in “Frontiers in Pharmacology” This review highlighted the pharmacological potential of Mor, noting its protective effects on the kidneys, liver, bones, nervous system, heart, digestive system, skin, and lungs, as well as its anti-obesity and anti-inflammatory properties, revealing areas for future research.
252 citations
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February 2018 in “npj Regenerative Medicine” This review explores recent advances in understanding molecular mechanisms of tissue regeneration in mammals and suggests potential therapeutic targets, but it reports no new clinical results.
225 citations
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April 2018 in “Journal of Investigative Dermatology” Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.
106 citations
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October 2016 in “Cell Stem Cell” This study found that PDGFA is critical for the proliferation and maintenance of adipocyte stem cells in skin but not other white adipose tissues, highlighting unique regulatory mechanisms in different tissue depots.
92 citations
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August 2017 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that newborn mouse skin organoids can robustly grow hair in vivo, while adult organoids require specific interventions to restore their hair-forming ability.
77 citations
,
August 2025 in “Signal Transduction and Targeted Therapy” This review highlights the potential of extracellular vesicle-based therapies for treating various diseases, but it also notes challenges like the lack of regulatory guidelines that hinder their clinical development.
51 citations
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September 2020 in “Cell Metabolism” This study highlights that the mammalian target of rapamycin complex 2 (mTORC2)-Akt signaling axis is essential for hair follicle stem cells to return to their niche and regenerate effectively by regulating metabolic pathways.
46 citations
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January 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Insig deficiency in the skin of mice causes cholesterol precursors to accumulate, leading to defective hair development and skin abnormalities, which were alleviated by simvastatin treatment.