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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Finasteride reduces movement issues in Parkinson's disease rats.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Estazolam reduces anxiety-like behavior in PTSD by increasing allopregnanolone levels.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Finasteride affects SRD5A2 gene pattern, possibly causing lasting side effects.

Glioblastoma cells can make androgens, which might help the tumor grow.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.

Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.

Taurine might help prevent hair loss caused by stress.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

The most effective treatments for hair loss are minoxidil, finasteride, PRP, and hair transplants, with steroids and immunosuppressants for autoimmune types.

Early NAS level changes affect alcohol consumption vulnerability.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

Progesterone and its metabolites affect myelin protein expression differently in male and female rat Schwann cells.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

Increasing TSPO in the brain reduces anxiety and depression.

Blocking neurosteroid production can lead to more seizures and faster epilepsy onset in rats.

Diabetic neuropathy in mice is linked to poor mitochondria function and lower brain hormone production.

Finasteride, a drug, can block the seizure-preventing effects of a hormone called progesterone in mice.