January 2026 in “Dermatologic Therapy” This review discusses female pattern hair loss as an early marker of hormonal imbalance and evaluates hormonal and lifestyle interventions, but reports no new clinical results.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review reports that alopecia, particularly alopecia areata, significantly impacts mental health and quality of life through stress and immune mechanisms, with treatments like Janus kinase inhibitors showing promise for improving both hair regrowth and psychological well-being.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review found significant psychosocial impacts of alopecia, noting that those with alopecia, particularly alopecia areata, experience higher rates of depression and anxiety. The review also highlighted new treatments like Janus kinase inhibitors that improve both hair regrowth and quality of life.
295 citations
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May 2016 in “Journal of the American Academy of Dermatology” This review examines the immunological aspects of alopecia areata, focusing on genetic, neuroimmunological, and immune privilege factors, but does not report new clinical findings.
286 citations
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August 2007 in “Journal of Clinical Investigation” This review examines the interplay of genetics and neuroimmunology in alopecia areata, highlighting its potential to inform broader autoimmunity research, but reports no new findings.
90 citations
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October 1998 in “Animal Reproduction Science” This study found that in captive mouflon rams, reproductive and physical maturation, marked by changes in hormone levels and physical attributes, progresses gradually across their life span, with sexual maturity tied closely to physical maturity.
54 citations
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March 2009 in “BioEssays” This review discusses the complex hormonal control of keratin expression in skin and its potential implications for treating skin and hair disorders, but reports no new clinical results.
49 citations
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May 2018 in “Endocrine” This study found that only eumenorrheic polycystic ovary syndrome patients showed a temporal coupling between kisspeptin and luteinizing hormone pulsatile secretions.
32 citations
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September 2011 in “Journal of Neuroendocrinology” In this study, inhibiting the formation of 5α-reduced steroids in pregnant rats shortened gestation time, reduced litter size, and impaired cognitive and neuroendocrine function in their juvenile offspring.
18 citations
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February 2020 in “Journal of pharmaceutical and biomedical analysis” This study using high-performance liquid chromatography reported that mice with more diverse gut microbiota had higher levels of specific compounds in hair compared to those with less diversity, with stress affecting certain plasma levels.
11 citations
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November 2021 in “International journal of molecular sciences” In this study, germ-free male mice showed altered levels of certain neuroactive steroids in the brain and periphery, suggesting microbiota may influence neuroendocrine pathways that support brain functioning.
6 citations
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April 2019 in “Russkij žurnal detskoj nevrologii” This study found that neuroendocrine and reproductive disorders were most commonly reported in women with epilepsy taking valproic acid, while newer antiepileptic drugs resulted in more favorable outcomes.
4 citations
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March 2023 in “PubMed” This article discusses the association between COVID-19 infection and hair loss and reports no new clinical findings on the link or underlying mechanisms involved.
3 citations
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September 2024 in “Journal of Pre-Clinical and Clinical Research” This study reviews the current understanding of psychiatric disorders in women with PCOS, finding links to the gut-brain axis, neurotransmitter and neuroendocrine dysfunction, and suggests the need for routine mental health screening in these patients.
1 citations
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April 2015 in “Russkij žurnal detskoj nevrologii” This study found that young women with epilepsy experienced various neuroendocrinal and reproductive side effects, with valproic acid showing the highest risk for teratogenic effects and associated disorders.
1 citations
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June 2012 in “Springer eBooks” This article discusses the potential of acupuncture as a complementary or alternative therapy for PCOS, highlighting experimental evidence of its positive effects on reproductive and metabolic function, but reports no new clinical results.
September 2022 in “Women's healthcare” This review discusses various aspects of polycystic ovary syndrome, including its prevalence, diagnosis, and treatment options, and reports no new empirical results.
July 2026 in “Archives of Dermatological Research” This study explores the potential of adaptogenic herbal extracts like ashwagandha, rhodiola, and schisandra in treating stress-induced dermatoses, noting their effects on modulating the HPA axis, reducing inflammation, and improving skin barrier function.
June 2026 in “International Journal of Drug Delivery Technology” This case study suggests that palash basti, a form of Ayurvedic treatment, may effectively manage polyendocrine metabolic ovarian syndrome by improving menstrual regularity and hormonal balance, though further studies are needed.
May 2026 in “International Journal of Current Pharmaceutical Review and Research” This article discusses the causes of polycystic ovary syndrome, including environmental pollutants, genetics, and oxidative stress, and explains how these factors contribute to symptoms like irregular menstrual cycles and obesity without reporting new clinical results.
January 2026 in “Asian Journal of Pharmacy and Pharmacology” This paper reviews the complex nature of polycystic ovary syndrome, highlighting the need for a personalized, multidisciplinary approach to its management, and reports no new clinical results.
September 2025 in “International Journal of Science and Research (IJSR)” This theoretical review analyzes how stress affects hair loss through hormonal and neural pathways, indicating that knowledgeable hairdressers could help in early detection and guide clients toward medical interventions, highlighting a potential collaboration between aesthetic care and medical treatment for stress-induced alopecia.
In this study, researchers found no significant differences in the serum levels of DHEAs, DHT, and testosterone between female patients with oral lichen planus and healthy controls, suggesting no neuroendocrine etiology is associated with this condition.
January 2025 in “International Journal of Forest Animal and Fisheries Research” This review found that while elevated DHEA levels are observed in some women with PCOS, especially those with hyperandrogenism, inconsistencies across studies suggest that standardized measurement and analyses are needed to clarify DHEA's role as a biomarker and factor in PCOS pathophysiology.
November 2022 in “Journal of Investigative Dermatology” This study found that human scalp hair follicles produce neurohormones and responded to GHRH stimulation by prolonging hair growth, suggesting a functional peripheral HPS neuroendocrine signaling axis in the skin.
October 2021 in “Journal of Advanced Biomedical and Pharmaceutical Sciences” This study reviews polycystic ovary syndrome and vitamin D, reporting no new results, and notes the involvement of vitamin D receptors and insulin in ovarian function.
January 2021 in “Deep Blue (University of Michigan)” This study found that LepRb neurons in the brain are important targets for androgen action and influence sex-specific differences in reproductive and metabolic regulation, implicating them in conditions such as polycystic ovary syndrome.
April 2020 in “Journal of the Endocrine Society” In this case study, the use of somatostatin analogues was effective in localizing and confirming a neuroendocrine lung tumor as the source of ectopic ACTH syndrome, leading to marked clinical improvement in a patient unable to undergo surgery.
June 2017 in “Acta Scientiae Veterinariae” This case report documents a cat with necrolytic migratory erythema due to glucagonoma and diabetes mellitus, highlighting similarities to glucagonoma syndrome in humans.
This review highlights the multifaceted roles of skin in immune and endocrine functions, stressing its contributions to psycho-immunological and psycho-endocrine responses, but presents no new research findings.