research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
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research Phenotypic Heterogeneity in Human Genetic Diseases: Ultrasensitivity-Mediated Threshold Effects as a Unifying Molecular Mechanism
Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.
research Recent Advances in Neuropeptide-Related Omics and Gene Editing: Spotlight on NPY and Somatostatin and Their Roles in Growth and Food Intake of Fish
New tools show that in fish, NPY increases feeding and somatostatin decreases it.
research Mineral Deficiencies: A Root Cause for Reduced Longevity in Mammals
Not getting enough minerals can lead to health problems and shorter lifespans.
research Chemistry, Pharmacology, and Therapeutic Potential of Decursin: A Promising Natural Lead for New Drug Discovery and Development
Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.
research Application of Non-Pharmacologic Therapy in Hair Loss Treatment and Hair Regrowth
Non-drug therapies show promise for hair regrowth but need more research.
research Malus Pumila Mill. Cv Annurca Apple Extract Might Be Therapeutically Useful Against Oxidative Stress and Patterned Hair Loss
Annurca apple extract may help treat hair loss and protect against oxidative stress.
research Proteins in Scalp Hair of Preschool Children
Hair proteins in preschool children and their mothers could indicate developmental changes and health status.
research A Systematic Review on Drug Re-Profiling/Re-Purposing
The document concludes that drug repurposing, which is reusing known medicines for new illnesses, can provide faster, cheaper treatment options for various serious diseases, including cancer, COVID-19, and rare diseases.
research Human Hair Follicle-Derived Mesenchymal Stem Cells Promote Tendon Repair in a Rabbit Achilles Tendinopathy Model
Human hair follicle stem cells help repair tendon injuries.
research Teriflunomide and Its Mechanism of Action in Multiple Sclerosis
Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.
research Neuroactive Steroids and Ethanol Exposure: Relevance to Ethanol Sensitivity and Alcohol Use Disorders Risk
Neuroactive steroids may affect the risk and treatment of alcohol use disorders.
research Dermatological Aspects of Primary Psychiatric Disorders
Psychological issues with skin problems worsen patients' lives and treatment.
research Latanoprost-Loaded Nanotransfersomes Designed For Scalp Administration Enhance Keratinocytes Proliferation
Latanoprost-loaded nanotransfersomes could help treat hair loss by promoting hair growth.
research Delayed Puberty: Diagnosis and Management of Congenital Idiopathic Hypogonadotropic Hypogonadism
A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.
research Current Concepts in Aesthetic Endocrinology
Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.
research Changes in Hydrophobic Proteins in Response to Biotin Administration in Serum of Infant Patients with Alopecia as Assessed by the Protein Micro-Sequencing Method
Biotin helps regulate proteins in the blood, which may explain its role in hair growth.
research Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine
The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.
research Pharmacophore Modeling and Three Dimensional Database Searching for Drug Design Using Catalyst: Recent Advances
The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.
research Association Between Serum Melatonin and Skin Aging in an Urban Population of Mongolia
Lower melatonin levels are linked to more skin aging.
research Stem Cell Secretome as a Mechanism for Restoring Hair Loss Due to Stress, Particularly Alopecia Areata: Narrative Review
Stem cells and their secretions could potentially treat stress-induced hair loss, but more human trials are needed.
research Therapeutic Potential of Hair Follicle-Derived Stem Cell Intranasal Transplantation in a Rat Model of Ischemic Stroke
Transplanted hair follicle stem cells improved brain function and reduced damage after a stroke in rats.
research Platelet-Rich Plasma for Urologic Conditions: An Early Call for Composition Reporting
The conclusion is that future trials should report specific details about the PRP composition to better understand its effects on urologic conditions.
research Hair Disorders
Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.
research The Genetics of Hair Shaft Disorders
The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
research Expansion of the Spectrum of ITGB6-Related Disorders to Adolescent Alopecia, Dentogingival Abnormalities, and Intellectual Disability
A rare ITGB6 gene variant causes intellectual disability, hair loss, and dental issues.
research Genetic Disorders and Defects in Vitamin D Action
Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.
research Hair Amino Acids: Normal Values and Results in Metabolic Errors
Hair amino acid levels can indicate metabolic disorders.
research Physical Inactivity Is a Disease Synonymous With a Non-Permissive Brain Disorder
Physical inactivity is a primary cause of many human illnesses.
research Diseases of Periocular Hair
The document concludes that periocular hair disorders have various causes and treatments, and proper evaluation by specialists is important for management and prognosis.