A Systematic Review on Drug Re-Profiling/Re-Purposing

August 2022 in “ IARS international research journal ”

Bharti Sharma, Dinesh Kumar Yadav

TLDR The document concludes that drug repurposing, which is reusing known medicines for new illnesses, can provide faster, cheaper treatment options for various serious diseases, including cancer, COVID-19, and rare diseases.

The document discusses the potential of drug repurposing, a process that provides patients with access to medications with known safety profiles more quickly and inexpensively than developing new drugs. This process has been used with drugs like Sildenafil, Chloroquine, and Metformin, which are now used in multiple disease models. Despite challenges, drug repurposing is a crucial part of drug rediscovery strategies, benefiting patients with various serious illnesses, including different types of cancer, the novel coronavirus (SARS-CoV-2), and some orphan diseases.

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