Search

everythinglearnresearchcommunity

for

Search:↓

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.

Androgens may block hair growth signals, targeting this could treat hair loss.

Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.

Minoxidil helps prevent stress-caused hair loss in mice.

Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.

Certain drugs can cause early hair growth in mice by affecting the nerves.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.

Scientists developed a method to grow human fetal skin and digits in a lab for 3-4 weeks, which could help study skin features and understand genetic interactions in tissue formation.

Lower growth factors linked to balding in androgenetic alopecia.

Mitochondrial therapy and platelet-rich plasma therapy both stimulated hair regrowth in aging mice, with mitochondrial therapy showing similar effectiveness to plasma therapy.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

Beige and leaden pigment genes act within melanocytes, affecting pigment patterns.

Inhibiting class I HDACs helps maintain hair growth ability in skin cells.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

Gamma rays did not change hair follicle density but increased white and hypopigmented hairs in mice.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.