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In this study, a mouse model with a PIK3CA gain-of-function mutation in Schwann cells revealed unique communication with neighboring cells and a glycolytic shift in peripheral nerves, and early alpelisib treatment significantly improved symptoms, though efficacy declined with delayed administration due to limited drug penetration.

This case report documents a 57-year-old man with nephrotic syndrome linked to recurrent chronic graft-versus-host disease and lupus-like symptoms, with improvement after cyclosporin and steroids; however, he died later from leukemia relapse.

In this case report, a young woman experienced acute kidney injury linked to the use of a hair straightening product containing glyoxylic acid, suggesting dermal absorption may lead to calcium oxalate nephropathy; this highlights the need for regulatory review and public health intervention.

This study found that minoxidil may protect against chemotherapy-induced peripheral neuropathy and potentially support hair recovery and tumor suppression in mouse models.

This case report describes a 68-year-old woman with metastatic breast cancer who experienced significant improvement in visual acuity after stopping tamoxifen, which was associated with bilateral optic neuropathies.

This study found that diazepam had an exaggerated effect on GABA-related inhibitory tone in diabetic neuropathic mice compared to normal mice, potentially due to mitochondrial dysfunction affecting neurosteroid synthesis.

In this case report, tofacitinib was initiated in a 20-year-old female with alopecia universalis resistant to topical treatments, but resulted in a mild peripheral neuropathy side effect.

This study found that decreased pressure sensitivity and 2-point discrimination at the scalp's vertex were significantly associated with androgenetic alopecia in men.

This article suggests a hypothesis that scalp neuropathy may contribute to androgenetic alopecia, focusing on the potential role of the arrector pili muscle's innervation in maintaining hair health.

This study found that diazepam has an exaggerated effect on GABAergic inhibitory tone in diabetic neuropathy mouse models, likely due to upregulated neurosteroidogenic enzymes responding to mitochondrial dysfunction.

This case study suggests a potential common inflammatory cause between insidious optic neuropathy and alopecia areata in a 4-year-old boy.

This study found that eliminating senescent cells using senolytic drugs effectively prevented and reversed paclitaxel-induced peripheral neuropathy in mice.

This study suggests that dihydrotestosterone plays a key role in the development of chronic allograft nephropathy, and inhibiting androgens may improve long-term kidney transplant outcomes.

This case report details an instance of acute kidney injury following the inhalation of hair dye during a hairstyle session.

This article presents a case of Werner syndrome complicated by idiopathic membranous nephropathy, suggesting a possible but unproven genetic link between the two conditions.

In this case study, a 25-year-old presented with symptoms of lupus but tested negative for antinuclear antibodies, complicating diagnosis. The researchers emphasize that comprehensive diagnostic approaches, beyond ANA testing, are vital for effectively identifying and treating lupus nephritis to avoid serious outcomes.

In this case report, researchers highlighted two instances of oxalate nephropathy secondary to enteric hyperoxaluria following small bowel surgeries, emphasizing the need to consider this condition in patients with unexplained renal decline and a history of bowel surgery due to its typically poor prognosis.

This review discusses the mechanisms of platinum-induced peripheral neuropathy related to reactive oxygen species and explores potential antioxidant therapies and nanotechnology approaches, but reports no new clinical results.

Cryotherapy and compression therapy might help prevent chemotherapy nerve damage, but more research is needed.

This study found that keratin intermediate filaments in the hair of GAN patients are altered, showing decreased diffraction signals and increased stiffness, strength, and extensibility.

This commentary reports the first case of small fiber neuropathy, mast cell activation syndrome, and pericarditis following mRNA-based SARS-CoV-2 vaccination in a previously healthy 66-year-old woman.

This case report describes a patient with autoimmune autonomic neuropathy associated with high-titer gAChR antibodies who developed selective pigmented hair loss during IV immunoglobulin treatment.

In this study, a new formulation of human placental extract showed antioxidant and neurite outgrowth activities, significantly reduced hair graying in mice, and alleviated neuropathy symptoms, suggesting potential therapeutic benefits.

In this case report, a 31-year-old woman with severe multisystem lupus vasculitis initially presented with generalized pain and rapidly worsening neuropathy, ultimately improving with cyclophosphamide and prednisolone treatment. The authors highlight diagnostic challenges, particularly in interpreting autoantibody results after IVIG therapy.

This study found that keratin intermediate filaments in the hair of patients with giant axonal neuropathy were structurally altered, resulting in hair that was stiffer, stronger, and more extensible.

This study concludes that dietary L-serine supplementation shows promise as a long-term therapy for hereditary sensory and autonomic neuropathy type 1, reducing neurotoxic 1-deoxysphingolipid levels and improving symptoms in severe cases.

This study observed that common skin changes in patients with type 2 diabetes included peripheral hair loss, xerosis, anhydrosis, and nail alterations, underscoring the importance of controlling blood sugar and foot care to prevent neuropathy complications.

This study suggests that finasteride may help alleviate high-fat diet-induced kidney damage in mice by reducing TMAO synthesis and regulating gut microbiota.

This case report describes severe myelosuppression and alopecia totalis in a 10-year-old boy after azathioprine treatment for IgA nephropathy, which resolved after stopping the drug and receiving granulocyte colony-stimulating factor.

This review discusses potential agents, including acetyl-L-carnitine and vitamins, for repurposing in managing chemotherapy-induced peripheral neuropathy and reports no clinical results; the authors emphasize the need for further research.