Severe Lupus Vasculitic Neuropathy

    November 2025 in “ Practical Neurology ”
    Apoorva Anil Kumar, Victor Jia Wei Zhang, Carine J Moezinia, Sarah Levy, Fernanda Ruiz, Sebastian Brandner, Frederick Schon, Hamid Modarres, Alexander M Rossor, Apoorva Anil Kumar, Victor Jia Wei Zhang, Carine J Moezinia, Sarah Levy, Fernanda Ruiz, Sebastian Brandner, Frederick Schon, Hamid Modarres, Alexander M Rossor
    TLDR Correct diagnosis and treatment of lupus vasculitis improved the woman's severe symptoms.
    The document discusses a case of a 31-year-old woman with severe lupus vasculitic neuropathy, presenting with generalized pain, weakness, transient joint symptoms, rash, and hair loss. Initially suspected of having Guillain–Barré syndrome, she was treated with intravenous immunoglobulin, but subsequent tests revealed strongly positive lupus and antiphospholipid antibody titres. She was diagnosed with severe multisystem lupus vasculitis affecting both the central and peripheral nervous systems and was treated with cyclophosphamide and prednisolone, leading to notable improvement. The case highlights the challenges in diagnosing and treating neurological lupus, particularly the under-recognition of peripheral neuropathy as a presenting symptom.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 22 results

      community 2 years of fin, 1.5 years of minoxidil, calling it quits. Thank you.

      in Shaved/buzzed  567 upvotes 2 years ago
      This user has been struggling with hair loss for the past two years and attempted to treat it using finasteride and minoxidil. Despite their efforts, they have not seen any improvement in their condition, so they have decided to shave or buzz their head instead. Others gave advice on other treatments that could be tried if desired.

      community Not everyone should immediately go on Fin if they are starting to bald

      in Finasteride/Dutasteride  21 upvotes 2 years ago
      The conversation suggests that people should consult a dermatologist to understand their type of hair loss before starting treatments like finasteride or dutasteride, especially if they have autoimmune issues or low DHT. Some participants believe in starting treatment like finasteride immediately if hair loss is due to DHT, while others recommend ruling out other causes and considering minoxidil first, especially for younger individuals.

      community Finasteride not working isnt it MPB?

      in Finasteride/Dutasteride  5 upvotes 1 year ago
      A user is concerned that finasteride isn't working for their hair loss, questioning if it's due to male pattern baldness or low iron levels. They are advised to take finasteride daily and get blood work done.

      community What are some other causes of hair loss?

      in Chat  8 upvotes 1 year ago
      The conversation discusses hair loss causes beyond male pattern baldness, mentioning treatments like ketoconazole, zinc shampoo, and finasteride. Stress-related hair loss (telogen effluvium) is also suggested.

    Similar Research

    5 / 1000+ results