Systemic Lupus Erythematosus With Acute Inflammatory Demyelinating Polyneuropathy: A Case Report and Review of the Literature

    Xiangling Li, Yanqiang Wang
    TLDR A woman with lupus and severe nerve damage improved with specific treatments.
    The document presented a case report of a 34-year-old Chinese female with systemic lupus erythematosus (SLE) who developed acute inflammatory demyelinating polyneuropathy (AIDP), characterized by acute bilateral leg weakness, paraparesis, and facial muscle paralysis. Laboratory tests confirmed SLE, and treatment with intravenous immunoglobulin, methylprednisolone, and cyclophosphamide led to improvement. The report highlighted the rarity of this comorbidity and emphasized the importance of early diagnosis and aggressive treatment for positive outcomes. The literature review underscored the need to consider autoimmune diseases like SLE in patients presenting with AIDP or Guillain-Barre Syndrome (GBS)-like symptoms.
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