Glomerular Membranous Nephropathy and Werner Syndrome: A Case Report

This case report described a 41-year-old woman with Werner syndrome (WS), a rare genetic disorder, who developed chronic renal failure due to idiopathic membranous nephropathy (IMN). The patient exhibited typical WS symptoms, including premature cataracts, sparse gray hair, and scleroderma-like skin changes. Her renal condition was managed conservatively, leading to improved proteinuria and stabilized renal function. This was the first documented case of WS associated with renal impairment showing histological evidence of glomerulonephritis. The study suggested a potential genetic link between WS and renal disease, though further research was needed to clarify this relationship.